• Interaction Score: 15.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein farnesyltransferase inhibitor
    Direct Interaction yes
    Trial Name tipifarnib, R115777,Zarnestra

  • Interaction Score: 8.51

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? True
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

  • Interaction Score: 0.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family Farnesyltransferase inhibitor
    Alteration HRAS:.

    PMIDs:
    None found


    Sources:
    CGI OncoKB

  • Interaction Score: 0.51

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family Farnesyltransferase inhibitor
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15122075


    Sources:
    PharmGKB