NSC-87833 |
RASTINON |
GLYCONON |
PRAMIDEX |
TOLBUTAMIDE |
ORINASE |
NSC-23813 |
N-(SULFONYL-P-METHYLBENZENE)-N'-N-BUTYLUREA |
1-BUTYL-3-(P-METHYLPHENYLSULFONYL)UREA |
1-BUTYL-3-(P-TOLYLSULFONYL)UREA |
3-(P-TOLYL-4-SULFONYL)-1-BUTYLUREA |
N-(P-METHYLBENZENESULFONYL)-N'-BUTYLUREA |
N-N-BUTYL-N'-TOSYLUREA |
1-P-TOLUENESULFONYL-3-BUTYLUREA |
N-BUTYL-N'-P-TOLUENESULFONYLUREA |
1-BUTYL-3-TOSYLUREA |
N-(4-METHYLBENZENESULFONYL)-N'-BUTYLUREA |
N-BUTYL-N'-(4-METHYLPHENYLSULFONYL)UREA |
ORINASE (TN) |
N-BUTYL-N'-(P-TOLYLSULFONYL)UREA |
TOLBUTAMIDUM |
TOLYLSULFONYLBUTYLUREA |
TOLBUTAMIDA |
N-(4-METHYLPHENYLSULFONYL)-N'-BUTYLUREA |
TOLBUTAMIDE SODIUM |
ORINASE® |
chembl:CHEMBL782 |
drugbank:01124 |
pubchem.compound:5505 |
chemidplus:64-77-7 |
rxcui:10635 |
Year of Approval | approved before 1982 |
Drug Class | hypoglycemic agents |
Drug Categories | tests for diabetes |
Drug Categories | sulfur compounds |
FDA Approval | Approved before 1982 |
Drug Class | small molecule |
Drug Indications | Hypoglycemic Agents |
Drug Groups | investigational |
Drug Categories | alimentary tract and metabolism |
Drug Categories | cytochrome p-450 cyp2c18 substrates |
Drug Categories | cytochrome p-450 cyp2c8 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | drugs that are mainly renally excreted |
Drug Categories | drugs used in diabetes |
Drug Categories | oat1/slc22a6 inhibitors |
Drug Categories | sulfonylureas |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sulfonylurea receptor 1, Kir6.2 blocker |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | None |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sulfonylurea receptor 1, Kir6.2 blocker |
Direct Interaction | yes |
Specific Action of the Ligand | None |
Orinase 1gm | Drug Brand |
Rastinon | Drug Brand |
Tolbutamide | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | investigational |
TOLBUTAMIDE | Primary Drug Name |
Drug Class | hypoglycemic agents |
Year of Approval | approved before 1982 |
Drug Indications | Hypoglycemic Agents |
Drug Class | small molecule |
FDA Approval | Approved before 1982 |
D06OIV | TTD Drug ID |
TOLBUTAMIDE | GuideToPharmacology Ligand Name |