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TRANDOLAPRIL Drug Record

  • Summary
  • Interactions
  • Claims
  • TRANDOLAPRIL chembl:CHEMBL1519 Approved

    Alternate Names:

    GOPTEN
    ODRIK
    INDOLAPRIL
    TRANDOLAPRIL
    RU-44570
    MAVIK
    MAVIK®
    TRANDOLAPRILUM
    CI-907
    drugbank:00519
    pubchem.compound:5484727
    chemidplus:87679-37-6
    rxcui:38454
    chembl:CHEMBL1519

    Drug Info:

    Year of Approval 1996
    Drug Class antihypertensive agents
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications antihypertensive agent
    (2 More Sources)

    Publications:

    Piepho, 2000, Overview of the angiotensin-converting-enzyme inhibitors., Am J Health Syst Pharm
    Song et al., 2002, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update., Clin Pharmacokinet
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Zhu HJ et al., 2009, Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril., Biochem Pharmacol
    Gong Y et al., 2015, PTPRD gene associated with blood pressure response to atenolol and resistant hypertension., J Hypertens
  • TRANDOLAPRIL   PTPRD

    Interaction Score: 8.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26425837


    Sources:
    PharmGKB

  • TRANDOLAPRIL   CES1

    Interaction Score: 3.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19185566


    Sources:
    PharmGKB

  • TRANDOLAPRIL   ACE

    Interaction Score: 2.62

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name trandolapril,Gopten, Mavik, Odrik
    Novel drug target Established target
    Mechanism of Interaction Angiotensin-converting enzyme inhibitor

    PMIDs:
    11030016 11929321 11752352


    Sources:
    TdgClinicalTrial ChemblInteractions TEND TTD

  • TEND: TRANDOLAPRIL

    • Version: 01-August-2011

    Alternate Names:
    TRANDOLAPRIL Primary Drug Name

    Drug Info:
    Drug Class antihypertensive agents
    Year of Approval 1996

    Publications:

  • TdgClinicalTrial: TRANDOLAPRIL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antihypertensive agent
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

  • PharmGKB: trandolapril

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Zhu HJ et al., 2009, Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril., Biochem Pharmacol
    Gong Y et al., 2015, PTPRD gene associated with blood pressure response to atenolol and resistant hypertension., J Hypertens

  • TTD: Trandolapril

    • Version: 2020.06.01

    Alternate Names:
    D0M5OC TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1519

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL1519

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21