• Interaction Score: 4.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type acute myeloid leukemia
    Response Type predicted – sensitive
    Approval Status Phase II

  • Interaction Score: 4.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    FDA

  • Interaction Score: 1.35

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Note that this Ki is below the detection limit of the assay.
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

  • Interaction Score: 0.71

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • Interaction Score: 0.53

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy BEZ235 + Venetoclax
    Indication/Tumor Type breast cancer
    Response Type no benefit

    PMIDs:
    27974663


    Sources:
    JAX-CKB

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Evidence Type Actionable
    Approval Status Preclinical - Cell culture
    Response Type no benefit

    PMIDs:
    27974663


    Sources:
    JAX-CKB

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type acute myeloid leukemia
    Response Type predicted – sensitive
    Approval Status Phase II

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Venetoclax + VX-11e
    Indication/Tumor Type colorectal cancer
    Response Type no benefit

    PMIDs:
    27974663


    Sources:
    JAX-CKB

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Dasatinib;Venetoclax
    Drug family BCR-ABL inhibitor 2nd gen;BCL2 inhibitor
    Alteration ABL1__BCR

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy BEZ235 + Venetoclax
    Indication/Tumor Type breast cancer
    Response Type no benefit

    PMIDs:
    27974663


    Sources:
    JAX-CKB

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA