WARFARIN Drug Record
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WARFARIN chembl:CHEMBL1464 Approved
Alternate Names:
WARFARIN NSC-59813 PANWARFIN 4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)COUMARIN MAREVAN® ZOOCOUMARIN COUMAFENE COUMADIN® rxcui:11289 chembl:CHEMBL1464 pubchem.compound:54678486 chemidplus:81-81-2 drugbank:00682 Drug Info:
Year of Approval approved before 1982 Drug Class anticoagulants Drug Categories rodenticides FDA Approval Approved before 1982 Drug Class small molecule Drug Indications Anticoagulants Drug Categories compounds used in a research, industrial, or household setting Drug Categories cytochrome p-450 cyp1a2 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 cyp2c18 substrates Drug Categories cytochrome p-450 cyp2c18 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 cyp2c19 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2c19 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 cyp2c8 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2c9 inducers Drug Categories cytochrome p-450 cyp2c9 inducers (weak) Drug Categories cytochrome p-450 cyp3a inducers Drug Categories cytochrome p-450 cyp3a substrates Drug Categories cytochrome p-450 cyp3a4 inducers Drug Categories cytochrome p-450 cyp3a4 inducers (weak) Drug Categories cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 enzyme inducers Drug Categories cytochrome p-450 enzyme inhibitors Drug Categories cytochrome p-450 substrates Drug Categories drugs that are mainly renally excreted Drug Categories drugs that are mainly renally excreted with narrow therapeutic index Drug Categories heterocyclic compounds, fused-ring Drug Categories narrow therapeutic index drugs Drug Categories vitamin k inhibitors Publications:
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target Specific Action of the Ligand Inhibition PMIDs:
20072124 21174619 21326313 26445138 14765195 18752379 21635147 24029542 25042728 23602689 16815312 28262345 20833980 17110455 22534826 17124101 17042764 21383771 22528326 29781049 24474498 15358623 25594941 16611310 27581200 27262824 25026456 28382498 21318593 17015052 16141794 18466099 25519826 25312789 19875892 16580898 17989110 16432637 31653973 19135231 16888441 27488176 21900891 19387626 22248286 17189218 22349464 9684798 17456829 16983400 19745563 17391071 26257249 31395958 20203262 17413769 21185752 18574025 22854539 29577257 20615525 26219158 17031720 26433837 24728385 22990331 28429387 22616655 23061746 16270629 25769357 18240904 23183958 17510308 21981797 20339978 19874474 18030307 15888487 26223945 19582440 15938684 17049586 20410877 15883587 21148049 17111199 26777610 25244877 28689179 17653141 17275317 20421126 25001883 16960144 15947090 16821005 17329985 25084205 18950464 11926893 12931134 20833655 29396738 24919870 22075505 19177029 20585834 19794411 22571356 19297219 18698879 11752352 16890578 18690342 23774101 22676192 23159229 22010099 27121899 25521356 16847429 22592842 24019055 23208322 14676821 14765194 23104259 23949431 19077919 28049362 16493479 25989350 29054760 29432897 23423913 24330000 21176721 16611750 28033245 20386359 17112295 15865594 17906972 16815313 15930419 16676068 21273734 29298995 22040439 15790782 11127854 22549502 17161452 18234403 21110192 15597574 23279643 23932037 18542936
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Interaction Types & Directionality:
n/a Interaction Info:
Trial Name - Novel drug target Established target
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Alternate Names:
81-81-2 CAS Number Apo-warfarin Drug Brand Coumadin Drug Brand Drug Info:
Drug Groups approved Drug Type small molecule Drug Categories 4-hydroxycoumarins Publications:
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- Version: January-2014
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Drug Info:
Drug Indications Anticoagulants Drug Class small molecule FDA Approval Approved before 1982 Publications:
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Drug Info:
Drug Class anticoagulants Year of Approval approved before 1982 Publications:
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C945 NCI drug code Drug Info:
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CHEMBL1464 ChEMBL Drug ID Drug Info:
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D0E3OF TTD Drug ID Drug Info:
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- Version: ChEMBL_27
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Drug Info:
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Drug Info:
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- Version: 29-September-2020
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Drug Info:
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