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ZANUBRUTINIB Drug Record

  • Summary
  • Interactions
  • Claims
  • ZANUBRUTINIB chembl:CHEMBL3936761 Antineoplastic

    Alternate Names:

    BGB-3111
    ZANUBRUTINIB
    BRUKINSA
    drugbank:15035
    chembl:CHEMBL3936761
    chemidplus:1691249-45-2
    pubchem.compound:135565884

    Drug Info:

    (0 More Sources)

    Publications:

    Tarantelli C et al., 2019, The Bruton tyrosine kinase inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents., Haematologica
    Tam CS et al., 2019, Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL., Blood
    Guo Y et al., 2019, Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase., J Med Chem
  • ZANUBRUTINIB   BTK

    Interaction Score: 8.53

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    30679329 31340982 31381333


    Sources:
    TTD

  • TTD: BGB-3111

    • Version: 2020.06.01

    Alternate Names:
    D0UT4W TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL3936761

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21