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ABCC1 Gene Record

  • Summary
  • Interactions
  • Claims
  • ABCC1 4363 Druggable Genome

    Alternate Names:

    4363
    ATP BINDING CASSETTE SUBFAMILY C MEMBER 1
    ABCC1
    ABC29
    ABCC
    GS-X
    MRP
    MRP1
    158343
    51
    ENSG00000103222
    OTTHUMG00000048267
    P33527
    MRP1_HUMAN
    MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1
    MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 (ATP-BINDING CASSETTE, SUB- FAMILY C, MEMBER 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P33527]
    PA244
    T11288
    DFNA77

    Gene Info:

    Target Class Transporters
    Target Subclass TC:3.A.1.208.8
    Human Readable Name DRUGGABLE GENOME
    Target Subclass Active_transporters
    Transmembrane Helix Count 16
    Target Main Class Transporters
    Target Subclass ABCC
    Interpro Short Name ABC_transptr_TM_dom
    Uniprot Status Swiss-Prot
    Interpro Name ABC transporter, transmembrane domain
    Interpro Type Domain
    Human Readable Name ABC TRANSPORTER
    Interpro Acc IPR001140
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    ABC TRANSPORTER
    DRUGGABLE GENOME

    Publications:

    Weiss J et al., 2007, Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors., Drug Metab Dispos
    Perrotton T et al., 2007, (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1., J Biol Chem
    Rappa et al., 2000, Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells., Anticancer Drug Des.
    Terashi et al., 2000, Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells., Antimicrob. Agents Chemother.
    Juvale K et al., 2012, 4-Substituted-2-phenylquinazolines as inhibitors of BCRP., Bioorg Med Chem Lett
    Utsunomiya et al., 2000, Comparison of the accumulation and efflux kinetics of technetium-99m sestamibi and technetium-99m tetrofosmin in an MRP-expressing tumour cell line., Eur J Nucl Med
    Martel et al., 1997, The MRD1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes., Leuk. Res.
    Xia et al., 2004, [Effects of hypoxia on expression of P-glycoprotein and multidrug resistance protein in human lung adenocarcinoma A549 cell line]., Zhonghua Yi Xue Za Zhi
    Coelho AV et al., 2013, ABCB1 and ABCC1 variants associated with virological failure of first-line protease inhibitors antiretroviral regimens in Northeast Brazil patients., J Clin Pharmacol
    Raggers et al., 1999, The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane., J. Cell. Sci.
    Bakos et al., 2000, Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions., Mol. Pharmacol.
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Depeille et al., 2004, Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects., Mol. Pharmacol.
    Evers et al., 2000, Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export., Br. J. Cancer
    Morrow et al., 1998, Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells., J. Biol. Chem.
    Chen et al., 2000, [Establishment of cisplatin-induced multidrug resistant human epithelial ovarian cancer cell line 3AO/cDDP and its expressions of multidrug resistance proteins]., Zhonghua Fu Chan Ke Za Zhi
    Olson et al., 2002, The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1)., AIDS
    Benderra et al., 1998, Role of the vacuolar H+-ATPase in daunorubicin distribution in etoposide-resistant MCF7 cells overexpressing the multidrug-resistance associated protein., Int. J. Oncol.
    Lorico et al., 1995, Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene., Cancer Res.
    Perloff et al., 2001, Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line., J Pharm Sci
    Hooijberg et al., 1999, Potent interaction of flavopiridol with MRP1., Br. J. Cancer
    Chu et al., 1999, Active efflux of CPT-11 and its metabolites in human KB-derived cell lines., J. Pharmacol. Exp. Ther.
    López-Rodríguez R et al., 2018, Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis., Sci Rep
    Lima A et al., 2015, Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?, Int J Mol Sci
    Mikkelsen TS et al., 2011, PharmGKB summary: methotrexate pathway., Pharmacogenet Genomics
    Warren RB et al., 2008, Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis., J Invest Dermatol
    Gourdeau et al., 2002, Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts., Cancer Chemother. Pharmacol.
    Goldsborough AS et al., 2011, Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin., J Med Chem
    Oshiro C et al., 2009, Taxane pathway., Pharmacogenet Genomics
    Hosoi et al., 1998, Effect of MDR antagonists on the cidal activity of vincristine for cells expressing MDR-1 is superior to those expressing MRP., Int. J. Oncol.
    Laochariyakul et al., 2003, Functional study of intracellular P-gp- and MRP1-mediated pumping of free cytosolic pirarubicin into acidic organelles in intrinsic resistant SiHa cells., Can. J. Physiol. Pharmacol.
    Wang et al., 1998, Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53., Cancer Res.
    Clinckers et al., 2005, Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxcarbazepine: concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity., J. Pharmacol. Exp. Ther.
    Wong IL et al., 2009, Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives., J Med Chem
    Wang et al., 2004, Annexin-I expression modulates drug resistance in tumor cells., Biochem. Biophys. Res. Commun.
    Seral et al., 2003, Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus., J. Antimicrob. Chemother.
    Wittgen HG et al., 2011, Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4., Drug Metab Dispos
    Gao C et al., 2012, Mechanistic studies on the absorption and disposition of scutellarin in humans: selective OATP2B1-mediated hepatic uptake is a likely key determinant for its unique pharmacokinetic characteristics., Drug Metab Dispos
    Gollapudi et al., 1997, Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells., Cancer Chemother. Pharmacol.
    Li M et al., 2018, ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia., Pharmacogenomics J
    Wojnowski L et al., 2005, NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity., Circulation
    Li et al., 1999, [Modulation of multiple drug resistance by nomegestrol acetate and droloxifene in K562/A02]., Zhonghua Xue Ye Xue Za Zhi
    Perez-Soler et al., 1997, Annamycin circumvents resistance mediated by the multidrug resistance-associated protein (MRP) in breast MCF-7 and small-cell lung UMCC-1 cancer cell lines selected for resistance to etoposide., Int. J. Cancer
    Zembruski NC et al., 2011, Interaction potential of etravirine with drug transporters assessed in vitro., Antimicrob Agents Chemother
    Bour-Dill et al., 2000, Determination of intracellular organelles implicated in daunorubicin cytoplasmic sequestration in multidrug-resistant MCF-7 cells using fluorescence microscopy image analysis., Cytometry
    Lee WY et al., 2010, Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells., J Nat Prod
    Hong et al., 2003, Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites., Biochem. Biophys. Res. Commun.
  • ANNAMYCIN   ABCC1

    Interaction Score: 2.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9096663


    Sources:
    NCI

  • DEXVERAPAMIL   ABCC1

    Interaction Score: 2.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17646169


    Sources:
    DTC

  • TROXACITABINE   ABCC1

    Interaction Score: 2.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12451476


    Sources:
    NCI

  • TIOPRONIN   ABCC1

    Interaction Score: 1.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21657271


    Sources:
    DTC

  • SULFINPYRAZONE   ABCC1

    Interaction Score: 0.93

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    9885294 10727523 11752352 15044619 10917554 9685354


    Sources:
    TdgClinicalTrial TEND TTD

  • SCUTELLARIN   ABCC1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22822035


    Sources:
    DTC

  • EMTRICITABINE   ABCC1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • (S)-VERAPAMIL   ABCC1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17646169


    Sources:
    DTC

  • MK-571   ABCC1

    Interaction Score: 0.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19725578


    Sources:
    DTC

  • DELAVIRDINE   ABCC1

    Interaction Score: 0.49

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • THYMIDINE   ABCC1

    Interaction Score: 0.49

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9379682


    Sources:
    NCI

  • NOVOBIOCIN   ABCC1

    Interaction Score: 0.49

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10901300


    Sources:
    NCI

  • DROLOXIFENE   ABCC1

    Interaction Score: 0.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11721384


    Sources:
    NCI

  • PROBENECID   ABCC1

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9182837


    Sources:
    NCI

  • RIMONABANT   ABCC1

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21511945


    Sources:
    DTC

  • ETOPOSIDE PHOSPHATE   ABCC1

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7671247


    Sources:
    NCI

  • PIRARUBICIN   ABCC1

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12897808


    Sources:
    NCI

  • IRINOTECAN HYDROCHLORIDE   ABCC1

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9918583


    Sources:
    NCI

  • TENIPOSIDE   ABCC1

    Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9865734


    Sources:
    NCI

  • LAMIVUDINE   ABCC1

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12218384 17172311 23996099


    Sources:
    DTC NCI PharmGKB

  • AZITHROMYCIN   ABCC1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12697643


    Sources:
    NCI

  • LOPINAVIR   ABCC1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23996099


    Sources:
    PharmGKB

  • RITONAVIR   ABCC1

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11745741 23996099


    Sources:
    NCI PharmGKB

  • ABACAVIR   ABCC1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • OFLOXACIN   ABCC1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10817732


    Sources:
    NCI

  • TENOFOVIR   ABCC1

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • PILOCARPINE   ABCC1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15860570


    Sources:
    NCI

  • EFAVIRENZ   ABCC1

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21189339 17172311


    Sources:
    DTC

  • ALVOCIDIB   ABCC1

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10496352


    Sources:
    NCI

  • MELPHALAN   ABCC1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14733945


    Sources:
    NCI

  • ADRIAMYCIN   ABCC1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15130309


    Sources:
    NCI

  • ERYTHROMYCIN   ABCC1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10817732


    Sources:
    NCI

  • VERAPAMIL   ABCC1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19725578 17646169


    Sources:
    DTC

  • NEVIRAPINE   ABCC1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • EPIGALOCATECHIN GALLATE   ABCC1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14511674


    Sources:
    NCI

  • 7-ETHYL-10-HYDROXYCAMPTOTHECIN   ABCC1

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27845419


    Sources:
    PharmGKB

  • BENZBROMARONE   ABCC1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • ZIDOVUDINE   ABCC1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23996099


    Sources:
    PharmGKB

  • CYCLOSPORINE   ABCC1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23017888 11189941


    Sources:
    DTC NCI

  • ETOPOSIDE   ABCC1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9472114 7671247


    Sources:
    NCI

  • INDOMETHACIN   ABCC1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20455578


    Sources:
    DTC

  • MONTELUKAST   ABCC1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • METHOTREXATE   ABCC1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29743634 26086825 21317831 18256692


    Sources:
    PharmGKB

  • DIPYRIDAMOLE   ABCC1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9664131


    Sources:
    NCI

  • DAUNORUBICIN   ABCC1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10655559


    Sources:
    NCI

  • DOCETAXEL   ABCC1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21151855


    Sources:
    PharmGKB

  • DOXORUBICIN   ABCC1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16330681


    Sources:
    PharmGKB

  • PACLITAXEL   ABCC1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21151855


    Sources:
    PharmGKB

  • VINCRISTINE   ABCC1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • CISPLATIN   ABCC1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11372415


    Sources:
    NCI

  • Ensembl: ENSG00000103222

    • Version: 101_38

    Alternate Names:
    ABCC1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P33527

    • Version: January-2014

    Alternate Names:
    ABCC1 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:3.A.1.208.8

    Publications:

  • HopkinsGroom: P33527

    • Version: 11-September-2012

    Alternate Names:
    P33527 Uniprot Accession
    ENSG00000103222 Ensembl Gene Id
    MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 Uniprot Protein Name

    Gene Info:
    Interpro Short Name ABC_transptr_TM_dom
    Uniprot Status Swiss-Prot
    Interpro Name ABC transporter, transmembrane domain

    Gene Categories:
    ABC TRANSPORTER, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000103222

    • Version: 26-July-2011

    Alternate Names:
    ABCC1 Display Id
    ENSG00000103222 Ensembl Gene Id
    MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 (ATP-BINDING CASSETTE, SUB- FAMILY C, MEMBER 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P33527] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TEND: P33527

    • Version: 01-August-2011

    Alternate Names:
    MRP1_HUMAN Uniprot Id
    ABCC1 Gene Symbol
    ENSG00000103222 Ensembl Gene Id

    Gene Info:
    Target Subclass Active_transporters
    Transmembrane Helix Count 16
    Target Main Class Transporters

    Publications:

  • PharmGKB: ABCC1

    • Version: 18-August-2020

    Alternate Names:
    PA244 PharmGKB ID

    Gene Info:

    Publications:
    Visscher H et al., 2013, Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children., Pediatr Blood Cancer
    Visscher H et al., 2012, Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children., J Clin Oncol
    Wojnowski L et al., 2005, NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity., Circulation

  • NCI: ABCC1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Utsunomiya et al., 2000, Comparison of the accumulation and efflux kinetics of technetium-99m sestamibi and technetium-99m tetrofosmin in an MRP-expressing tumour cell line., Eur J Nucl Med
    Hooijberg et al., 1999, Potent interaction of flavopiridol with MRP1., Br. J. Cancer
    Seral et al., 2003, Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus., J. Antimicrob. Chemother.

  • DTC: ABCC1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Weiss J et al., 2007, Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors., Drug Metab Dispos
    Perrotton T et al., 2007, (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1., J Biol Chem
    Zembruski NC et al., 2011, Interaction potential of etravirine with drug transporters assessed in vitro., Antimicrob Agents Chemother

  • HingoraniCasas: ENSG00000103222

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000103222 Gene Symbol
    ABCC1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: ABCC1

    • Version: 01-February-2022

    Alternate Names:
    MRP GO Gene Synonym
    MRP1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    ABC TRANSPORTER

    Publications:

  • TTD: Multidrug resistance-associated protein 1

    • Version: 2020.06.01

    Alternate Names:
    ABCC1 TTD Gene Abbreviation
    T11288 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: ABCC1

    • Version: 01-February-2022

    Alternate Names:
    Multidrug resistance-associated protein 1 Gene Name
    P33527 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21