• ACVR2A 92 Druggable Genome

    Alternate Names:

    92
    ACTIVIN A RECEPTOR TYPE 2A
    ACVR2A
    ACTRII
    ACVR2
    102581
    173
    ENSG00000121989
    OTTHUMG00000150603
    P27037
    1791
    ACTIVIN RECEPTOR TYPE II PRECURSOR (EC 2.7.1.37) (ACTR-II) (ACTRIIA). [SOURCE:UNIPROT/SWISSPROT;ACC:P27037]
    ACVR2_HUMAN
    NP_001607
    NM_001616
    Activin receptor type IIA
    T47366
    Activin receptor type-2A

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name Type II receptor serine/threonine kinases
    GuideToPharmacology Gene Category ID 319
    Target Class Receptors
    Target Subclass EC:2.7.11.30
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 31.9

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Binding

    PMIDs:
    None found


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name ACE-011
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

    • Version: 101_38

    Alternate Names:
    ACVR2A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ACVR2_HUMAN Display Id
    ENSG00000121989 Ensembl Gene Id
    ACTIVIN RECEPTOR TYPE II PRECURSOR (EC 2.7.1.37) (ACTR-II) (ACTRIIA). [SOURCE:UNIPROT/SWISSPROT;ACC:P27037] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    ACVR2A Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass EC:2.7.11.30

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    173 HUGO Gene ID
    173 HUGO Gene Symbol
    activin A receptor type 2A HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Type II receptor serine/threonine kinases
    GuideToPharmacology Gene Category ID 319

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000121989 Gene Symbol
    ACVR2A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    92 Gene ID
    ACTRII dGene Synonym
    ACVR2 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    ACVR2A TTD Gene Abbreviation
    T47366 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    ACVR2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Activin receptor type-2A Gene Name
    P27037 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: