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ADCY1 Gene Record

  • Summary
  • Interactions
  • Claims
  • ADCY1 107 Druggable Genome

    Alternate Names:

    107
    ADENYLATE CYCLASE 1
    ADCY1
    AC1
    DFNB44
    103072
    232
    ENSG00000164742
    OTTHUMG00000155420
    Q08828
    ADCY1_HUMAN
    ADENYLATE CYCLASE, TYPE I (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 1) (CA(2+)/CALMODULIN ACTIVATED ADENYLYL CYCLASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08828]
    ADENYLATE CYCLASE TYPE 1
    PA24560
    T63609

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR001054
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase
    Uniprot Status Swiss-Prot
    Interpro Short Name A/G_cyclase
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem
    International Consortium on Lithium Genetics (ConLi+Gen). et al., 2018, Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study., JAMA Psychiatry
  • CHEMBL401844   ADCY1

    Interaction Score: 15.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18630896


    Sources:
    DTC

  • LITHIUM   ADCY1

    Interaction Score: 1.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29121268


    Sources:
    PharmGKB

  • Ensembl: ENSG00000164742

    • Version: 101_38

    Alternate Names:
    ADCY1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000164742

    • Version: 26-July-2011

    Alternate Names:
    ADCY1 Display Id
    ADENYLATE CYCLASE, TYPE I (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 1) (CA(2+)/CALMODULIN ACTIVATED ADENYLYL CYCLASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08828] Description
    ENSG00000164742 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q08828

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000164742 Ensembl Gene Id
    ADCY1_HUMAN Uniprot Id
    Q08828 Uniprot Accession

    Gene Info:
    Interpro Acc IPR001054
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • PharmGKB: ADCY1

    • Version: 18-August-2020

    Alternate Names:
    PA24560 PharmGKB ID

    Gene Info:

    Publications:
    International Consortium on Lithium Genetics (ConLi+Gen). et al., 2018, Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study., JAMA Psychiatry

  • DTC: ADCY1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem

  • HingoraniCasas: ENSG00000164742

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000164742 Gene Symbol
    ADCY1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: ADCY1

    • Version: 19.3

    Alternate Names:
    ENSG00000164742 Ensembl Gene ID
    AC1 Human Protein Atlas Gene Synonym
    DFNB44 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • TTD: Adenylate cyclase type 1

    • Version: 2020.06.01

    Alternate Names:
    ADCY1 TTD Gene Abbreviation
    T63609 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21