DGIdb - ADCY2 Gene Record

ADCY2 108 Druggable Genome

Alternate Names:

108
ADENYLATE CYCLASE 2
ADCY2
AC2
HBAC2
103071
233
ENSG00000078295
OTTHUMG00000090476
Q08462
ADCY2_HUMAN
ADENYLATE CYCLASE TYPE 2
ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462]
adenylyl cyclase 2
PA24561
1279

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Interpro Name	Adenylyl cyclase class-3/4/guanylyl cyclase
Interpro Acc	IPR001054
Uniprot Status	Swiss-Prot
Uniprot Evidence	1: Evidence at protein level
Interpro Type	Domain
Interpro Short Name	A/G_cyclase
Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	Adenylyl cyclases (ACs)
GuideToPharmacology Gene Category ID	257

(3 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
ENZYME

Publications:

van Huis-Tanja LH et al., 2015, Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients., Pharmacogenet Genomics
Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem

CHEMBL401844 ADCY2

Interaction Score: 15.95

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18630896

Sources:
DTC
CAPECITABINE ADCY2

Interaction Score: 1.77

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25815774

Sources:
PharmGKB

Ensembl: ENSG00000078295
- Version: 101_38
Alternate Names:

ADCY2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: Q08462
- Version: 11-September-2012
Alternate Names:

ADCY2 Uniprot Gene Name

ENSG00000078295 Ensembl Gene Id

ADENYLATE CYCLASE TYPE 2 Uniprot Protein Name

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase

Interpro Acc IPR001054

Gene Categories:

DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000078295

Version: 26-July-2011

Alternate Names:

ADCY2 Display Id

ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462] Description

ENSG00000078295 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

GuideToPharmacology: 108
- Version: 29-September-2020
Alternate Names:

233 HUGO Gene ID

233 HUGO Gene Symbol

adenylate cyclase 2 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Adenylyl cyclases (ACs)

GuideToPharmacology Gene Category ID 257

Gene Categories:

ENZYME

Publications:
PharmGKB: ADCY2
- Version: 18-August-2020
Alternate Names:

PA24561 PharmGKB ID

Gene Info:

Publications:

van Huis-Tanja LH et al., 2015, Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients., Pharmacogenet Genomics
DTC: ADCY2
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem
Pharos: ADCY2
- Version: 01-May-2021
Alternate Names:

Adenylate cyclase type 2 Gene Name

Q08462 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

ADCY2	Uniprot Gene Name
ENSG00000078295	Ensembl Gene Id
ADENYLATE CYCLASE TYPE 2	Uniprot Protein Name

ADCY2	Display Id
ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462]	Description
ENSG00000078295	Ensembl Gene Id

233	HUGO Gene ID
233	HUGO Gene Symbol
adenylate cyclase 2	HUGO Gene Name

ADCY2 Gene Record

ADCY2 108 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

CHEMBL401844 ADCY2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18630896

Sources: DTC

CAPECITABINE ADCY2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 25815774

Sources: PharmGKB

Ensembl: ENSG00000078295

Alternate Names: ADCY2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: Q08462

Alternate Names: ADCY2 Uniprot Gene Name ENSG00000078295 Ensembl Gene Id ADENYLATE CYCLASE TYPE 2 Uniprot Protein Name

Gene Info: Human Readable Name DRUGGABLE GENOME Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase Interpro Acc IPR001054

Gene Categories: DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000078295

Alternate Names: ADCY2 Display Id ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462] Description ENSG00000078295 Ensembl Gene Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

GuideToPharmacology: 108

Alternate Names: 233 HUGO Gene ID 233 HUGO Gene Symbol adenylate cyclase 2 HUGO Gene Name

Gene Info: GuideToPharmacology Gene Category Name Adenylyl cyclases (ACs) GuideToPharmacology Gene Category ID 257

Gene Categories: ENZYME

Publications:

PharmGKB: ADCY2

Alternate Names: PA24561 PharmGKB ID

Gene Info:

Publications: van Huis-Tanja LH et al., 2015, Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients., Pharmacogenet Genomics

DTC: ADCY2

Alternate Names:

Gene Info:

Publications: Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem

Pharos: ADCY2

Alternate Names: Adenylate cyclase type 2 Gene Name Q08462 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
18630896

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
25815774

Sources:
PharmGKB

Alternate Names:

ADCY2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ADCY2 Uniprot Gene Name

ENSG00000078295 Ensembl Gene Id

ADENYLATE CYCLASE TYPE 2 Uniprot Protein Name

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase

Interpro Acc IPR001054

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ADCY2 Display Id

ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462] Description

ENSG00000078295 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

233 HUGO Gene ID

233 HUGO Gene Symbol

adenylate cyclase 2 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Adenylyl cyclases (ACs)

GuideToPharmacology Gene Category ID 257

Gene Categories:

ENZYME

Alternate Names:

PA24561 PharmGKB ID

Publications:

van Huis-Tanja LH et al., 2015, Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients., Pharmacogenet Genomics

Publications:

Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem

Alternate Names:

Adenylate cyclase type 2 Gene Name

Q08462 UniProt ID

Gene Categories:

ENZYME