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ADCY2 Gene Record

  • Summary
  • Interactions
  • Claims
  • ADCY2 108 Druggable Genome

    Alternate Names:

    108
    ADENYLATE CYCLASE 2
    ADCY2
    AC2
    HBAC2
    103071
    233
    ENSG00000078295
    OTTHUMG00000090476
    Q08462
    ADCY2_HUMAN
    ADENYLATE CYCLASE TYPE 2
    ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462]
    PA24561

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase
    Interpro Acc IPR001054
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Short Name A/G_cyclase
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    van Huis-Tanja LH et al., 2015, Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients., Pharmacogenet Genomics
    Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem
  • CHEMBL401844   ADCY2

    Interaction Score: 15.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18630896


    Sources:
    DTC

  • CAPECITABINE   ADCY2

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25815774


    Sources:
    PharmGKB

  • Ensembl: ENSG00000078295

    • Version: 101_38

    Alternate Names:
    ADCY2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q08462

    • Version: 11-September-2012

    Alternate Names:
    ADCY2 Uniprot Gene Name
    ENSG00000078295 Ensembl Gene Id
    ADENYLATE CYCLASE TYPE 2 Uniprot Protein Name

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase
    Interpro Acc IPR001054

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000078295

    • Version: 26-July-2011

    Alternate Names:
    ADCY2 Display Id
    ADENYLATE CYCLASE, TYPE II (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE 2) (ADENYLYL CYCLASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q08462] Description
    ENSG00000078295 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • PharmGKB: ADCY2

    • Version: 18-August-2020

    Alternate Names:
    PA24561 PharmGKB ID

    Gene Info:

    Publications:
    van Huis-Tanja LH et al., 2015, Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients., Pharmacogenet Genomics

  • DTC: ADCY2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Schlicker C et al., 2008, Structure-based development of novel adenylyl cyclase inhibitors., J Med Chem

  • Pharos: ADCY2

    • Version: 01-February-2022

    Alternate Names:
    Adenylate cyclase type 2 Gene Name
    Q08462 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21