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ADCYAP1R1 Gene Record

  • Summary
  • Interactions
  • Claims
  • ADCYAP1R1 117 Druggable Genome

    Alternate Names:

    117
    ADCYAP RECEPTOR TYPE I
    ADCYAP1R1
    PAC1
    PAC1R
    PACAPR
    PACAPRI
    102981
    242
    ENSG00000078549
    OTTHUMG00000023884
    P41586
    PACR_HUMAN
    PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR
    PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PACAP TYPE I RECEPTOR) (PACAP-R-1). [SOURCE:UNIPROT/SWISSPROT;ACC:P41586]
    PACAP type I receptor
    T92185

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Short Name GPCR_2_secretin-like
    Interpro Acc IPR000832
    Interpro Name GPCR, family 2, secretin-like
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

    Jamen et al., 2002, Pituitary adenylate cyclase-activating polypeptide receptors mediating insulin secretion in rodent pancreatic islets are coupled to adenylate cyclase but not to PLC., Endocrinology
    Martin et al., 2003, Morphine withdrawal is modified in pituitary adenylate cyclase-activating polypeptide type I-receptor-deficient mice., Brain Res. Mol. Brain Res.
  • NALOXONE   ADCYAP1R1

    Interaction Score: 5.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12573539


    Sources:
    NCI

  • INSULIN   ADCYAP1R1

    Interaction Score: 1.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11897681


    Sources:
    NCI

  • Ensembl: ENSG00000078549

    • Version: 101_38

    Alternate Names:
    ADCYAP1R1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P41586

    • Version: 11-September-2012

    Alternate Names:
    ADCYAP1R1 Uniprot Gene Name
    PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR Uniprot Protein Name
    117 Entrez Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Short Name GPCR_2_secretin-like

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000078549

    • Version: 26-July-2011

    Alternate Names:
    PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PACAP TYPE I RECEPTOR) (PACAP-R-1). [SOURCE:UNIPROT/SWISSPROT;ACC:P41586] Description
    ADCYAP1R1 Display Id
    ENSG00000078549 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • NCI: ADCYAP1R1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Jamen et al., 2002, Pituitary adenylate cyclase-activating polypeptide receptors mediating insulin secretion in rodent pancreatic islets are coupled to adenylate cyclase but not to PLC., Endocrinology
    Martin et al., 2003, Morphine withdrawal is modified in pituitary adenylate cyclase-activating polypeptide type I-receptor-deficient mice., Brain Res. Mol. Brain Res.
    Zhang et al., 2005, Effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on IL-6, IL-8, and MCP-1 expression in human retinal pigment epithelial cell line., Curr. Eye Res.

  • HingoraniCasas: ENSG00000078549

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000078549 Gene Symbol
    ADCYAP1R1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: ADCYAP1R1

    • Version: 27-Jun-2013

    Alternate Names:
    117 Gene ID
    PAC1 dGene Synonym
    PAC1R dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • TTD: PACAP type I receptor

    • Version: 2020.06.01

    Alternate Names:
    PAC1R TTD Gene Abbreviation
    T92185 TTD Target ID

    Gene Info:

    Publications:

  • GO: ADCYAP1R1

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21