147 |
ADRENOCEPTOR ALPHA 1B |
ADRA1B |
ADRA1 |
ALPHA1BAR |
104220 |
278 |
ENSG00000170214 |
OTTHUMG00000130327 |
P35368 |
Alpha-1B adrenoreceptor |
Alpha-1B adrenergic receptor |
Alpha-1B adrenoceptor |
ADA1B_HUMAN |
ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR) (ALPHA 1B- ADRENORECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P35368] |
PA33 |
Adrenergic receptor alpha-1B |
T29500 |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
Target Main Class | Receptors |
Target Subclass | GPCR |
Human Readable Name | DRUGGABLE GENOME |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Target Class | Receptors |
Interpro Type | Family |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Uniprot Status | Swiss-Prot |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Interpro Acc | IPR000276 |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Adrenergic receptor alpha-1 agonist |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha-1 agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha-1 agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Adrenergic receptor alpha-1 agonist |
other/unknown |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha-1 agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha-1 agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
Direct Interaction | yes |
n/a |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Trial Name | PSD-503, phenylephrine |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
n/a |
Trial Name | Serdolect |
Novel drug target | Established target |
n/a |
Trial Name | Vyvanse |
Novel drug target | Established target |
n/a |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
Novel drug target | Established target |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha agonist |
Direct Interaction | yes |
n/a |
Trial Name | - |
Novel drug target | Established target |
n/a |
Trial Name | AGN-214868 |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor alpha agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-1 antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adrenergic receptor agonist |
Direct Interaction | yes |
ADRA1B | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR) (ALPHA 1B- ADRENORECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P35368] | Description |
ADRA1B | Display Id |
ENSG00000170214 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
147 | Entrez Gene Id |
P35368 | Uniprot Accession |
ADRA1B | Uniprot Gene Name |
Interpro Type | Family |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | GPCR, rhodopsin-like, 7TM |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
P35368 | Uniprot Accession |
ENSG00000170214 | Ensembl Gene Id |
ADRA1B | Gene Symbol |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
Target Main Class | Receptors |
ADRA1B | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
ENSG00000170214 | Gene Symbol |
ADRA1B | Ensembl Id |
DRUGGABLE GENOME |
ADRA1B | GENE_SYMBOL |
Alpha-1B adrenergic receptor | UNIPROT |
Alpha-1B adrenoreceptor | UNIPROT |
PA33 | PharmGKB ID |
147 | Gene ID |
ADRA1 | dGene Synonym |
ALPHA1BAR | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
ADRA1B | TTD Gene Abbreviation |
T29500 | TTD Target ID |
G PROTEIN COUPLED RECEPTOR |