• AKR1D1 6718 Druggable Genome

    Alternate Names:

    6718
    ALDO-KETO REDUCTASE FAMILY 1 MEMBER D1
    AKR1D1
    3o5bred
    CBAS2
    SRD5B1
    604741
    388
    ENSG00000122787
    OTTHUMG00000155787
    3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6) (DELTA(4)-3- KETOSTEROID 5-BETA-REDUCTASE) (ALDO-KETO REDUCTASE FAMILY 1 MEMBER D1). [SOURCE:UNIPROT/SWISSPROT;ACC:P51857]
    P51857
    3-OXO-5-BETA-STEROID 4-DEHYDROGENASE
    AK1D1_HUMAN
    PA24681

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Target Class Enzymes
    Target Subclass EC:1.3.1.3
    Interpro Short Name Aldo/ket_red
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Aldo/keto reductase
    Interpro Acc IPR001395
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 9.81

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name YM-152, finasteride
    Novel drug target Established target

    PMIDs:
    19515843


    Sources:
    TdgClinicalTrial

    • Version: 101_38

    Alternate Names:
    AKR1D1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6) (DELTA(4)-3- KETOSTEROID 5-BETA-REDUCTASE) (ALDO-KETO REDUCTASE FAMILY 1 MEMBER D1). [SOURCE:UNIPROT/SWISSPROT;ACC:P51857] Description
    AKR1D1 Display Id
    ENSG00000122787 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    AKR1D1 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:1.3.1.3

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    AK1D1_HUMAN Uniprot Id
    P51857 Uniprot Accession
    ENSG00000122787 Ensembl Gene Id

    Gene Info:
    Interpro Short Name Aldo/ket_red
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 18-August-2020

    Alternate Names:
    PA24681 PharmGKB ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    3-oxo-5-beta-steroid 4-dehydrogenase Gene Name
    P51857 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications: