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ALB Gene Record

  • Summary
  • Interactions
  • Claims
  • ALB 213 Druggable Genome

    Alternate Names:

    213
    ALBUMIN
    ALB
    HSA
    PRO0883
    PRO0903
    PRO1341
    103600
    399
    ENSG00000163631
    OTTHUMG00000129919
    SERUM ALBUMIN
    T63068
    FDAHT
    P02768

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    DRUGGABLE GENOME

    Publications:

    Blair et al., 2004, Population pharmacokinetics of raltitrexed in patients with advanced solid tumours., Br J Clin Pharmacol
    Ishii T et al., 2010, Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin., Bioorg Med Chem
    Buttar D et al., 2010, A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions., Bioorg Med Chem
    Samari F et al., 2012, Investigation of the interaction between amodiaquine and human serum albumin by fluorescence spectroscopy and molecular modeling., Eur J Med Chem
    Thorarensen A et al., 2007, Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor., Bioorg Med Chem Lett
    Ikenoue et al., 2000, Disease-induced alterations in plasma drug-binding proteins and their influence on drug binding percentages in dogs., Vet Q
    Ishizuka T et al., 2012, Paraoxonase 1 as a major bioactivating hydrolase for olmesartan medoxomil in human blood circulation: molecular identification and contribution to plasma metabolism., Drug Metab Dispos
    Chubarov AS et al., 2011, Synthesis and characterization of fluorinated homocysteine derivatives as potential molecular probes for ¹⁹F magnetic resonance spectroscopy and imaging., Bioorg Med Chem Lett
    Zhang SL et al., 2014, Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP., Bioorg Med Chem Lett
    Chen X et al., 2015, Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin., Eur J Med Chem
  • COCHINCHINENIN C   ALB

    Interaction Score: 5.89

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25734332


    Sources:
    DTC

  • CHEMBL1945287   ALB

    Interaction Score: 5.89

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21632244


    Sources:
    DTC

  • EPIGALLOCATECHIN   ALB

    Interaction Score: 5.89

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20598557


    Sources:
    DTC

  • GADOFOSVESET   ALB

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • OLMESARTAN MEDOXOMIL   ALB

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22086979


    Sources:
    DTC

  • AMODIAQUINE HYDROCHLORIDE   ALB

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22658498


    Sources:
    DTC

  • IODIPAMIDE   ALB

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • [19F]-HALOPERIDOL   ALB

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • EPICATECHIN GALLATE   ALB

    Interaction Score: 1.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20598557


    Sources:
    DTC

  • RALTITREXED   ALB

    Interaction Score: 0.84

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15025739


    Sources:
    NCI

  • FLUCONAZOLE   ALB

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25301772


    Sources:
    DTC

  • (-)-EPICATECHIN   ALB

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20598557


    Sources:
    DTC

  • NAPROXEN   ALB

    Interaction Score: 0.49

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10682387


    Sources:
    NCI

  • PHENYLBUTAZONE   ALB

    Interaction Score: 0.49

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20869876


    Sources:
    DTC

  • PYROGALLOL   ALB

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20598557


    Sources:
    DTC

  • DICLOFENAC   ALB

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17560104


    Sources:
    DTC

  • OXYPHENBUTAZONE   ALB

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • EPIGALOCATECHIN GALLATE   ALB

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20598557


    Sources:
    DTC

  • DIAZEPAM   ALB

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20869876


    Sources:
    DTC

  • WARFARIN   ALB

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17560104


    Sources:
    DTC

  • EBSELEN   ALB

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Ensembl: ENSG00000163631

    • Version: 101_38

    Alternate Names:
    ALB Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TTD: Serum albumin

    • Version: 2020.06.01

    Alternate Names:
    ALB TTD Gene Abbreviation
    T63068 TTD Target ID

    Gene Info:

    Publications:
    Shimmura S et al., 2003, Albumin as a tear supplement in the treatment of severe dry eye., Br J Ophthalmol

  • NCI: ALB

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Blair et al., 2004, Population pharmacokinetics of raltitrexed in patients with advanced solid tumours., Br J Clin Pharmacol
    Araki et al., 1992, Immunocytochemical localization of alpha-fetoprotein in the developing and carbon tetrachloride-treated rat liver., Acta Anat (Basel)
    Ikenoue et al., 2000, Disease-induced alterations in plasma drug-binding proteins and their influence on drug binding percentages in dogs., Vet Q

  • DTC: ALB

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Ishii T et al., 2010, Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin., Bioorg Med Chem
    Buttar D et al., 2010, A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions., Bioorg Med Chem
    Thorarensen A et al., 2007, Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor., Bioorg Med Chem Lett

  • HingoraniCasas: ENSG00000163631

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000163631 Gene Symbol
    ALB Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: ALB

    • Version: 01-February-2022

    Alternate Names:
    Serum albumin Gene Name
    P02768 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21