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ALDH2 217 Druggable GenomeClinically Actionable
Alternate Names:
217 ALDEHYDE DEHYDROGENASE 2 FAMILY (MITOCHONDRIAL) ALDH2 ALDH-E2 ALDHI ALDM 100650 404 ENSG00000111275 OTTHUMG00000169603 P05091 ALDH2_HUMAN ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (EC 1.2.1.3) (ALDH CLASS 2) (ALDHI) (ALDH-E2). [SOURCE:UNIPROT/SWISSPROT;ACC:P05091] 2595 ALDH class 2 aldehyde dehydrogenase 2 family member PA24696 Mitochondrial aldehyde dehydrogenase T44282 NP_001122302 NM_001128830 Gene Info:
Target Subclass 1.2.1.3 Target Main Class Enzymes Interpro Type Domain Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot Uniprot Evidence 1: Evidence at protein level Interpro Short Name Aldehyde_DH_dom Interpro Name Aldehyde dehydrogenase domain Interpro Acc IPR015590 Target Class Enzymes Target Subclass EC:1.2.1.3 Gene Biotype PROTEIN_CODING GuideToPharmacology Gene Category Name 1.-.-.- Oxidoreductases GuideToPharmacology Gene Category ID 840 Gene Categories: Category Details
DRUGGABLE GENOME CLINICALLY ACTIONABLE ENZYME Publications:
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Details of Interaction <i>In vitro</i> inhibition of recombinant human mitochondrial alcohol dehydrogenase Endogenous Drug? False -
Interaction Score: 4.25
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Interaction Score: 1.96
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Interaction Score: 1.64
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Aldehyde dehydrogenase inhibitor Trial Name -
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- Version: 101_38
Alternate Names:
ALDH2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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Alternate Names:
217 Entrez Gene Id P05091 Uniprot Accession ALDH2_HUMAN Uniprot Id Gene Info:
Target Subclass 1.2.1.3 Target Main Class Enzymes Publications:
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- Version: January-2014
Alternate Names:
ALDH2 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:1.2.1.3 Publications:
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- Version: 26-July-2011
Alternate Names:
ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (EC 1.2.1.3) (ALDH CLASS 2) (ALDHI) (ALDH-E2). [SOURCE:UNIPROT/SWISSPROT;ACC:P05091] Description ALDH2 Display Id ENSG00000111275 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
ALDH2 Uniprot Gene Name ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL Uniprot Protein Name P05091 Uniprot Accession Gene Info:
Interpro Type Domain Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
404 HUGO Gene ID 404 HUGO Gene Symbol aldehyde dehydrogenase 2 family member HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name 1.-.-.- Oxidoreductases GuideToPharmacology Gene Category ID 840 Gene Categories:
ENZYME Publications:
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Alternate Names:
PA24696 PharmGKB ID Gene Info:
Publications:
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Alternate Names:
Gene Info:
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- Version: chembl_23
Alternate Names:
ALDM GENE_SYMBOL ALDH2 GENE_SYMBOL Aldehyde dehydrogenase, mitochondrial UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000111275 Gene Symbol ALDH2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 2020.06.01
Alternate Names:
ALDH2 TTD Gene Abbreviation T44282 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Aldehyde dehydrogenase, mitochondrial Gene Name P05091 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications:
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- Version: 04-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: