• ANGPT2 285 Druggable Genome

    Alternate Names:

    285
    ANGIOPOIETIN 2
    ANGPT2
    AGPT2
    ANG2
    601922
    485
    ENSG00000091879
    OTTHUMG00000090365
    ANGIOPOIETIN-2 PRECURSOR (ANG-2). [SOURCE:UNIPROT/SWISSPROT;ACC:O15123]
    Angiopoietin-2
    ANG-2
    O15123
    ANGP2_HUMAN
    T21960

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Fibrinogen_a/b/g_C
    Interpro Name Fibrinogen, alpha/beta/gamma chain, C-terminal globular
    Interpro Type Domain
    Interpro Acc IPR002181
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name FIBRINOGEN
    Uniprot Status Swiss-Prot
    Target Class Ligand
    Target Subclass Ligand
    Target Subclass Serpin-family
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    DRUGGABLE GENOME
    FIBRINOGEN
  • Interaction Score: 47.84

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Angiopoietin-2 inhibitor
    Direct Interaction yes
    Trial Name REGN910

    PMIDs:
    None found


  • Interaction Score: 15.95

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 7.97

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Angiopoietin-2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.97

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16104024


    Sources:
    NCI