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AQP1 Gene Record

  • Summary
  • Interactions
  • Claims
  • AQP1 358 Druggable Genome

    Alternate Names:

    358
    AQUAPORIN 1 (COLTON BLOOD GROUP)
    AQP1
    AQP-CHIP
    CHIP28
    CO
    107776
    633
    ENSG00000240583
    OTTHUMG00000023944
    Collagen
    T68934

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

    Abu-Hamdah et al., 2004, Regulation of the water channel aquaporin-1: isolation and reconstitution of the regulatory complex., Cell Biol. Int.
    Xiang et al., 2004, Acetazolamide inhibits aquaporin-1 protein expression and angiogenesis., Acta Pharmacol. Sin.
    Mu et al., 2003, [Differential protein analysis in rat renal proximal tubule epithelial cells in response to acetazolamide and its relation with the inhibition of AQP1]., Yao Xue Xue Bao
    Oshio et al., 2003, Aquaporin-1 deletion reduces osmotic water permeability and cerebrospinal fluid production., Acta Neurochir. Suppl.
    Ma et al., 2004, Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte., Acta Pharmacol. Sin.
    Xiang et al., 2002, Acetazolamide suppresses tumor metastasis and related protein expression in mice bearing Lewis lung carcinoma., Acta Pharmacol. Sin.
  • ACETAZOLAMIDE   AQP1

    Interaction Score: 11.24

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    15169637 12830709 14753499 14704128 12147198


    Sources:
    NCI

  • GLYBURIDE   AQP1

    Interaction Score: 2.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14759764


    Sources:
    NCI

  • COLLAGENASE CLOSTRIDIUM HISTOLYTICUM   AQP1

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Ensembl: ENSG00000240583

    • Version: 101_38

    Alternate Names:
    AQP1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: AQP1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Abu-Hamdah et al., 2004, Regulation of the water channel aquaporin-1: isolation and reconstitution of the regulatory complex., Cell Biol. Int.
    Badran et al., Expression and regulation of aquaporins 1, 8, and 9 in the testis, efferent ducts, and epididymis of adult rats and during postnatal development., J. Androl.
    Ma et al., 2004, Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte., Acta Pharmacol. Sin.

  • HingoraniCasas: ENSG00000240583

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000240583 Gene Symbol
    AQP1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TTD: Collagen

    • Version: 2020.06.01

    Alternate Names:
    CO TTD Gene Abbreviation
    T68934 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21