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ARID1A Gene Record

  • Summary
  • Interactions
  • Claims
  • ARID1A 8289 Clinically Actionable

    Alternate Names:

    8289
    AT-RICH INTERACTION DOMAIN 1A
    ARID1A
    B120
    BAF250
    BAF250a
    BM029
    C1orf4
    CSS2
    ELD
    MRD14
    OSA1
    P270
    SMARCF1
    hELD
    hOSA1
    603024
    11110
    ENSG00000117713
    OTTHUMG00000004004
    6559

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    CLINICALLY ACTIONABLE

    Publications:

    Miller et al., 2016, Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib., Mol. Cancer Ther.
    Shen J et al., 2018, ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade., Nat Med
    Hu C et al., 2018, Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinoma., J Hepatol
  • ATEZOLIZUMAB   ARID1A

    Interaction Score: 1.9

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29736026


    Sources:
    CIViC

  • NIVOLUMAB   ARID1A

    Interaction Score: 1.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29736026


    Sources:
    CIViC

  • PEMBROLIZUMAB   ARID1A

    Interaction Score: 1.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29736026


    Sources:
    CIViC

  • DASATINIB   ARID1A

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27364904


    Sources:
    CIViC

  • SORAFENIB   ARID1A

    Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29113912


    Sources:
    CIViC

  • Ensembl: ENSG00000117713

    • Version: 101_38

    Alternate Names:
    ARID1A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • CIViC: ARID1A

    • Version: 14-September-2020

    Alternate Names:
    8289 Entrez Gene ID
    6559 CIViC Gene ID

    Gene Info:

    Publications:
    Bitler et al., 2015, Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers., Nat. Med.
    Miller et al., 2016, Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib., Mol. Cancer Ther.
    Hu C et al., 2018, Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinoma., J Hepatol

  • Tempus: ARID1A

    • Version: 11-November-2018

    Alternate Names:
    ARID1A Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • MskImpact: ARID1A

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • FoundationOneGenes: ARID1A

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: ARID1A

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • Oncomine: ARID1A

    • Version: v3

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21