• ASIC3 9311 Druggable Genome

    Alternate Names:

    9311
    ACID SENSING ION CHANNEL SUBUNIT 3
    ASIC3
    ACCN3
    DRASIC
    SLNAC1
    TNaC1
    611741
    101
    ENSG00000213199
    OTTHUMG00000158685
    Q9UHC3
    686
    ASIC3_HUMAN
    ACID-SENSING ION CHANNEL 3

    Gene Info:

    GuideToPharmacology Gene Category Name Acid-sensing (proton-gated) ion channels (ASICs)
    GuideToPharmacology Gene Category ID 118
    Target Class transporter
    Target Subclass TC:1.A.6.1.2
    Interpro Name Na+ channel, amiloride-sensitive
    Human Readable Name ION CHANNEL
    Interpro Acc IPR001873
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Short Name Na+channel_ASC
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 15.95

    Interaction Types & Directionality:
    activator (activating)
    agonist (activating)

    Interaction Info:
    Endogenous Drug? False
    Details of Interaction at pH 7.4
    Specific Action of the Ligand None

    PMIDs:
    21143836


  • Interaction Score: 7.97

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Endogenous Drug? False
    Details of Interaction at pH 7.4
    Specific Action of the Ligand None

    PMIDs:
    None found


  • Interaction Score: 3.99

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Human ASIC3 expressed in HEK293 cells
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 2.66

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.72

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction transient component
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.53

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Endogenous Drug? False
    Details of Interaction transient component only - sustained component enhanced by 200μM amiloride at pH 4
    Specific Action of the Ligand None

    PMIDs:
    None found


  • Interaction Score: 0.33

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction sustained component
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.11

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Endogenous Drug? False
    Details of Interaction sustained component
    Specific Action of the Ligand None

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    ASIC3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ACID-SENSING ION CHANNEL 3 Uniprot Protein Name
    ASIC3_HUMAN Uniprot Id
    ENSG00000213199 Ensembl Gene Id

    Gene Info:
    Interpro Name Na+ channel, amiloride-sensitive
    Human Readable Name ION CHANNEL
    Interpro Acc IPR001873

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    ACCN3 Gene Symbol

    Gene Info:
    Target Class transporter
    Target Subclass TC:1.A.6.1.2

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    101 HUGO Gene ID
    101 HUGO Gene Symbol
    acid sensing ion channel subunit 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Acid-sensing (proton-gated) ion channels (ASICs)
    GuideToPharmacology Gene Category ID 118

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000213199 Gene Symbol
    ASIC3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Acid-sensing ion channel 3 Gene Name
    Q9UHC3 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: