• ATP1A2 477 Druggable Genome

    Alternate Names:

    477
    ATPASE NA+/K+ TRANSPORTING SUBUNIT ALPHA 2
    ATP1A2
    FHM2
    MHP2
    182340
    800
    ENSG00000018625
    OTTHUMG00000024080
    KIAA0778
    Na(+)/K(+) ATPase alpha-2 subunit
    Sodium/potassium-transporting ATPase subunit alpha-2
    Sodium pump subunit alpha-2
    834
    P50993
    sodium/potassium-transporting ATPase subunit α-2
    SODIUM/POTASSIUM-TRANSPORTING ATPASE ALPHA-2 CHAIN PRECURSOR (EC 3.6.3.9) (SODIUM PUMP 2) (NA+/K+ ATPASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P50993]
    AT1A2_HUMAN
    PA30796

    Gene Info:

    GuideToPharmacology Gene Category Name Na<sup>+</sup>/K<sup>+</sup>-ATPases
    GuideToPharmacology Gene Category ID 158
    Human Readable Name DRUGGABLE GENOME
    Interpro Name ATPase, P-type cation exchange, alpha subunit
    Human Readable Name ION CHANNEL
    Uniprot Status Swiss-Prot
    Interpro Name ATPase, P-type cation-transporter, N-terminal
    Interpro Short Name ATPase_P-typ_cation-exchng_asu
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR006069
    Human Readable Name TRANSPORTER
    Interpro Type Domain
    Interpro Acc IPR006068
    Interpro Name ATPase, P-type cation-transporter, C-terminal
    Interpro Short Name ATPase_P-typ_cation-transptr_N
    Interpro Type Family
    Interpro Short Name ATPase_P-typ_cation-transptr_C
    Interpro Acc IPR004014
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    ION CHANNEL
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Interaction Score: 1.59

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Sodium/potassium-transporting ATPase inhibitor

    PMIDs:
    None found


  • Interaction Score: 1.42

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/potassium-transporting ATPase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.71

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/potassium-transporting ATPase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.38

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/potassium-transporting ATPase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

    • Version: 101_38

    Alternate Names:
    ATP1A2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000018625 Ensembl Gene Id
    SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-2 Uniprot Protein Name
    P50993 Uniprot Accession

    Gene Info:
    Interpro Name ATPase, P-type cation exchange, alpha subunit
    Human Readable Name ION CHANNEL
    Uniprot Status Swiss-Prot

    Gene Categories:
    TRANSPORTER, ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000018625 Ensembl Gene Id
    SODIUM/POTASSIUM-TRANSPORTING ATPASE ALPHA-2 CHAIN PRECURSOR (EC 3.6.3.9) (SODIUM PUMP 2) (NA+/K+ ATPASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P50993] Description
    ATP1A2 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    800 HUGO Gene ID
    800 HUGO Gene Symbol
    ATPase Na+/K+ transporting subunit alpha 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Na<sup>+</sup>/K<sup>+</sup>-ATPases
    GuideToPharmacology Gene Category ID 158

    Gene Categories:
    TRANSPORTER

    Publications:

    • Version: chembl_23

    Alternate Names:
    KIAA0778 GENE_SYMBOL
    ATP1A2 GENE_SYMBOL
    Sodium/potassium-transporting ATPase subunit alpha-2 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000018625 Gene Symbol
    ATP1A2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 18-August-2020

    Alternate Names:
    PA30796 PharmGKB ID

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000018625 Ensembl Gene ID
    FHM2 Human Protein Atlas Gene Synonym
    MHP2 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER, ENZYME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Sodium/potassium-transporting ATPase subunit alpha-2 Gene Name
    P50993 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications: