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AURKA Gene Record

  • Summary
  • Interactions
  • Claims
  • AURKA 6790 Druggable GenomeClinically ActionableDrug Resistance

    Alternate Names:

    6790
    AURORA KINASE A
    AURKA
    AIK
    ARK1
    AURA
    BTAK
    PPP1R47
    STK15
    STK6
    STK7
    603072
    11393
    ENSG00000087586
    OTTHUMG00000032796
    O14965
    AURKA_HUMAN
    Aurora 2
    hARK1
    Serine/threonine-protein kinase 6
    Serine/threonine-protein kinase 15
    AYK1
    Breast tumor-amplified kinase
    Aurora/IPL1-related kinase 1
    ARK-1
    IAK1
    Serine/threonine-protein kinase aurora-A
    AIRK1
    Aurora-related kinase 1
    BE0000991
    61
    O14695
    Aurora A/B/C
    Aurora A
    SERINE/THREONINE-PROTEIN KINASE 6 (EC 2.7.1.37) (SERINE/THREONINE KINASE 15) (AURORA/IPL1-RELATED KINASE 1) (AURORA-RELATED KINASE 1) (HARK1) (AURORA-A) (BREAST-TUMOR-AMPLIFIED KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:O14965]
    1936
    NP_003591
    NM_003600
    T87675
    AURORA2

    Gene Info:

    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Human Readable Name KINASE
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Acc IPR002290
    Uniprot Evidence 1: Evidence at protein level
    Target Class Enzymes
    Target Subclass EC:2.7.11.1
    GuideToPharmacology Gene Category Name Aurora kinase (Aur) family
    GuideToPharmacology Gene Category ID 557
    CancerCommons Reported Gene Name Aurora Kinase
    Gene Biotype PROTEIN_CODING
    (20 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUG RESISTANCE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

    Tamotsu et al., 2015, Correlation of Aurora-A expression with the effect of chemoradiation therapy on esophageal squamous cell carcinoma., BMC Cancer
    Xu et al., 2014, Aurora-A contributes to cisplatin resistance and lymphatic metastasis in non-small cell lung cancer and predicts poor prognosis., J Transl Med
    Cee VJ et al., 2010, Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor., J Med Chem
    Manfredi MG et al., 2007, Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase., Proc Natl Acad Sci U S A
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.
    Wang S et al., 2010, Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors., J Med Chem
    Angiolini M et al., 2010, Structure-based optimization of potent PDK1 inhibitors., Bioorg Med Chem Lett
    Anand et al., 2003, AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol., Cancer Cell
    Zheng et al., 2014, Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer., Oncogene
    Rolf MG et al., 2015, In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib., Pharmacol Res Perspect
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
  • CHEMBL521105   AURKA

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL223147   AURKA

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL495758   AURKA

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • ANILINOPYRIMIDINE1   AURKA

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL472193   AURKA

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • TAS-119   AURKA

    Interaction Score: 1.96

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    TTD ChemblInteractions

  • MK-5108   AURKA

    Interaction Score: 1.63

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    PMIDs:
    None found


    Sources:
    TTD TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • PF-03814735   AURKA

    Interaction Score: 1.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor

    PMIDs:
    None found


    Sources:
    TALC MyCancerGenome ChemblInteractions

  • CHEMBL522891   AURKA

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • NERVIANO   AURKA

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20621725


    Sources:
    DTC

  • DANUSERTIB   AURKA

    Interaction Score: 0.98

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor
    Notes

    PMIDs:
    None found


    Sources:
    TTD TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • AMG-900   AURKA

    Interaction Score: 0.98

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor
    Direct Interaction yes
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


    Sources:
    ClearityFoundationClinicalTrial TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • AT-9283   AURKA

    Interaction Score: 0.53

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial TTD DrugBank TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • KW-2449   AURKA

    Interaction Score: 0.39

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology ChemblInteractions

  • MK-6592   AURKA

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DUBERMATINIB   AURKA

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • GSK-1070916   AURKA

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • EUPATORIN   AURKA

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TTP-607   AURKA

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ENMD-2076   AURKA

    Interaction Score: 0.29

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name ENMD-2076
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor

    PMIDs:
    None found


    Sources:
    ClearityFoundationClinicalTrial TdgClinicalTrial TTD TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • NORHARMANE   AURKA

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BARASERTIB   AURKA

    Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


    Sources:
    DTC GuideToPharmacology

  • MLN-8054   AURKA

    Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor
    Specific Action of the Ligand Inhibition

    PMIDs:
    20684549 17360485


    Sources:
    DTC DrugBank GuideToPharmacology ChemblInteractions

  • ALISERTIB   AURKA

    Interaction Score: 0.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor
    Notes

    PMIDs:
    None found


    Sources:
    CancerCommons MyCancerGenomeClinicalTrial DTC TdgClinicalTrial DrugBank TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • SNS-314   AURKA

    Interaction Score: 0.19

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name SNS-314
    Novel drug target Novel Target
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor

    PMIDs:
    None found


    Sources:
    DTC TdgClinicalTrial TTD DrugBank TALC MyCancerGenome GuideToPharmacology ChemblInteractions

  • CHEMBL1765740   AURKA

    Interaction Score: 0.16

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • DIMETHYLADENINE   AURKA

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   AURKA

    Interaction Score: 0.1

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    19035792


    Sources:
    DTC TdgClinicalTrial TTD TALC GuideToPharmacology ChemblInteractions

  • ENZASTAURIN   AURKA

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DrugBank

  • XL-228   AURKA

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name XL228
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • CHEMBL202721   AURKA

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AZD-1152-HQPA   AURKA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   AURKA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    DTC DrugBank TALC MyCancerGenome ChemblInteractions

  • CHEMBL578061   AURKA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • JNJ-7706621   AURKA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    DTC GuideToPharmacology

  • ILORASERTIB   AURKA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


    Sources:
    DTC TTD GuideToPharmacology ChemblInteractions

  • ENMD-981693   AURKA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • RG-1530   AURKA

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


    Sources:
    DTC GuideToPharmacology ChemblInteractions

  • CHEMBL546797   AURKA

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   AURKA

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora inhibitor

    PMIDs:
    20462263


    Sources:
    DTC ChemblInteractions

  • TAMOXIFEN   AURKA

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24166501


    Sources:
    CIViC

  • AST-487   AURKA

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HESPERADIN   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

  • OSI-632   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GO-6976   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GSK-269962A   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PAZOPANIB   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • KENPAULLONE   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PACLITAXEL   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12559175


    Sources:
    CIViC

  • CISPLATIN   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25924824 25082261


    Sources:
    CIViC

  • PF-00562271   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    DTC GuideToPharmacology

  • FLUOROURACIL   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25924824


    Sources:
    CIViC

  • ENTRECTINIB   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GW441756X   AURKA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   AURKA

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SORAFENIB   AURKA

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   AURKA

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FOSTAMATINIB   AURKA

    Interaction Score: 0.01

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

  • Ensembl: ENSG00000087586

    • Version: 101_38

    Alternate Names:
    AURKA Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: O14965

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000087586 Ensembl Gene Id
    AURKA_HUMAN Uniprot Id
    O14965 Uniprot Accession

    Gene Info:
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: O14965

    • Version: January-2014

    Alternate Names:
    AURKA Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.1

    Publications:

  • CancerCommons: AURKA

    • Version: 25-July-2013

    Alternate Names:
    6790 Entrez Gene ID

    Gene Info:
    CancerCommons Reported Gene Name Aurora Kinase

    Publications:

  • TdgClinicalTrial: O14695

    • Version: January-2014

    Alternate Names:
    AURKA Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.1

    Publications:

  • RussLampel: ENSG00000087586

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000087586 Ensembl Gene Id
    SERINE/THREONINE-PROTEIN KINASE 6 (EC 2.7.1.37) (SERINE/THREONINE KINASE 15) (AURORA/IPL1-RELATED KINASE 1) (AURORA-RELATED KINASE 1) (HARK1) (AURORA-A) (BREAST-TUMOR-AMPLIFIED KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:O14965] Description
    AURKA Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GuideToPharmacology: 6790

    • Version: 29-September-2020

    Alternate Names:
    11393 HUGO Gene ID
    11393 HUGO Gene Symbol
    aurora kinase A HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Aurora kinase (Aur) family
    GuideToPharmacology Gene Category ID 557

    Gene Categories:
    ENZYME

    Publications:

  • CIViC: AURKA

    • Version: 14-September-2020

    Alternate Names:
    6790 Entrez Gene ID
    61 CIViC Gene ID

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:
    Mignogna et al., 2016, Aurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients., J Ovarian Res
    Zheng et al., 2014, Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer., Oncogene
    Tamotsu et al., 2015, Correlation of Aurora-A expression with the effect of chemoradiation therapy on esophageal squamous cell carcinoma., BMC Cancer

  • DrugBank: BE0000991

    • Version: 5.1.7

    Alternate Names:
    AURKA DrugBank Gene Name
    O14965 UniProt Accession
    6790 Entrez Gene Id

    Gene Info:

    Publications:
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

  • DTC: AURKA

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.
    Kishore AH et al., 2008, Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system., J Med Chem
    Angiolini M et al., 2010, Structure-based optimization of potent PDK1 inhibitors., Bioorg Med Chem Lett

  • TALC: AURORA A

    • Version: 12-May-2016

    Alternate Names:
    AURORA A Gene Symbol

    Gene Info:

    Publications:

  • MyCancerGenome: AURKA

    • Version: 20-Jun-2017

    Alternate Names:
    6790 Entrez Gene Id
    AURKA MyCancerGenome Gene Symbol
    Aurora A MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000087586

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000087586 Gene Symbol
    AURKA Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: AIK

    • Version: chembl_23

    Alternate Names:
    AIRK1 GENE_SYMBOL
    ARK1 GENE_SYMBOL
    AURA GENE_SYMBOL

    Gene Info:

    Publications:

  • Pharos: AURKA

    • Version: 03-September-2020

    Alternate Names:
    Aurora kinase A Gene Name
    O14965 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: AURKA

    • Version: 05-September-2020

    Alternate Names:
    AIK GO Gene Synonym
    AIRK1 GO Gene Synonym
    ARK1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • Tempus: AURKA

    • Version: 11-November-2018

    Alternate Names:
    AURKA Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • dGene: AURKA

    • Version: 27-Jun-2013

    Alternate Names:
    6790 Gene ID
    AIK dGene Synonym
    ARK1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Aurora kinase A

    • Version: 2020.06.01

    Alternate Names:
    AURKA TTD Gene Abbreviation
    T87675 TTD Target ID

    Gene Info:

    Publications:

  • MskImpact: AURKA

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • ClearityFoundationClinicalTrial: AURKA

    • Version: 15-June-2013

    Alternate Names:

    Gene Info:

    Publications:

  • MyCancerGenomeClinicalTrial: AURKA

    • Version: 30-February-2014

    Alternate Names:

    Gene Info:

    Publications:

  • FoundationOneGenes: AURKA

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: AURKA

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13