9212 |
AURORA KINASE B |
AURKB |
AIK2 |
AIM-1 |
AIM1 |
ARK-2 |
ARK2 |
AurB |
IPL1 |
PPP1R48 |
STK-1 |
STK12 |
STK5 |
aurkb-sv1 |
aurkb-sv2 |
604970 |
11390 |
ENSG00000178999 |
OTTHUMG00000108189 |
Q96GD4 |
AIRK2 |
STK1 |
AURKB_HUMAN |
SERINE/THREONINE-PROTEIN KINASE 12 (EC 2.7.1.37) (AURORA- AND IPL1- LIKE MIDBODY-ASSOCIATED PROTEIN 1) (AIM-1) (AURORA/IPL1-RELATED KINASE 2) (AURORA-RELATED KINASE 2) (STK-1) (AURORA-B). [SOURCE:UNIPROT/SWISSPROT;ACC:Q96GD4] |
AURORA- AND IPL1-LIKE MIDBODY-ASSOCIATED PROTEIN 1 |
AURORA/IPL1-RELATED KINASE 2 |
AURORA-RELATED KINASE 2 |
Serine/threonine-protein kinase 5 |
Serine/threonine-protein kinase 12 |
Aurora 1 |
Serine/threonine-protein kinase aurora-B |
Aurora B |
Aurora A/B/C |
T46781 |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.1 |
Human Readable Name | KINASE |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR002290 |
Interpro Type | Domain |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Uniprot Evidence | 1: Evidence at protein level |
Gene Biotype | PROTEIN_CODING |
KINASE |
SERINE THREONINE KINASE |
HISTONE MODIFICATION |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
ENZYME |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Novel drug target | Novel Target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora-B inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
AURKB | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
Q96GD4 | Uniprot Accession |
9212 | Entrez Gene Id |
AURKB_HUMAN | Uniprot Id |
Human Readable Name | KINASE |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
Uniprot Status | Swiss-Prot |
KINASE, DRUGGABLE GENOME |
ENSG00000178999 | Ensembl Gene Id |
SERINE/THREONINE-PROTEIN KINASE 12 (EC 2.7.1.37) (AURORA- AND IPL1- LIKE MIDBODY-ASSOCIATED PROTEIN 1) (AIM-1) (AURORA/IPL1-RELATED KINASE 2) (AURORA-RELATED KINASE 2) (STK-1) (AURORA-B). [SOURCE:UNIPROT/SWISSPROT;ACC:Q96GD4] | Description |
AURKB | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
AURKB | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.1 |
AURKB | TTD Gene Abbreviation |
T46781 | TTD Target ID |
ENSG00000178999 | Gene Symbol |
AURKB | Ensembl Id |
DRUGGABLE GENOME |
AURORA B | Gene Symbol |
9212 | Entrez Gene Id |
AURKB | MyCancerGenome Gene Symbol |
Aurora A/B/C | MyCancerGenome Reported Gene Name |
AIM1 | GENE_SYMBOL |
AIRK2 | GENE_SYMBOL |
ARK2 | GENE_SYMBOL |
ENSG00000178999 | Ensembl Gene ID |
Aik2 | Human Protein Atlas Gene Synonym |
AIM-1 | Human Protein Atlas Gene Synonym |
ENZYME |
AIK2 | GO Gene Synonym |
AIM1 | GO Gene Synonym |
AIRK2 | GO Gene Synonym |
SERINE THREONINE KINASE, HISTONE MODIFICATION |
AURKB | Gene Symbol |
CLINICALLY ACTIONABLE |
9212 | Gene ID |
AIK2 | dGene Synonym |
AIM-1 | dGene Synonym |
KINASE, SERINE THREONINE KINASE |
Aurora kinase B | Gene Name |
Q96GD4 | UniProt ID |
KINASE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |