DGIdb - BDNF Gene Record

BDNF 627 Druggable Genome

Alternate Names:

627
BRAIN DERIVED NEUROTROPHIC FACTOR
BDNF
ANON2
BULN2
113505
1033
ENSG00000176697
OTTHUMG00000178797
brain-derived neurotrophic factor
PA31891
T93122

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

GROWTH FACTOR
DRUGGABLE GENOME

Publications:

Mannion et al., 1999, Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity., Proc. Natl. Acad. Sci. U.S.A.
Xu et al., 2008, BDNF gene is a genetic risk factor for schizophrenia and is related to the chlorpromazine-induced extrapyramidal syndrome in the Chinese population., Pharmacogenet. Genomics
Wick et al., 2004, Chemotherapy-induced cell death in primary cerebellar granule neurons but not in astrocytes: in vitro paradigm of differential neurotoxicity., J. Neurochem.
Gao X et al., 2017, Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese., OMICS
Iamjan SA et al., 2015, BDNF (Val66Met) genetic polymorphism is associated with vulnerability for methamphetamine dependence., Pharmacogenomics
Haerian BS, 2013, BDNF rs6265 polymorphism and drug addiction: a systematic review and meta-analysis., Pharmacogenomics
Paskowitz et al., 2004, BDNF reduces the retinal toxicity of verteporfin photodynamic therapy., Invest. Ophthalmol. Vis. Sci.
Tabuchi et al., 2000, Differential activation of brain-derived neurotrophic factor gene promoters I and III by Ca2+ signals evoked via L-type voltage-dependent and N-methyl-D-aspartate receptor Ca2+ channels., J. Biol. Chem.
Salloum NC et al., 2014, Towards the clinical implementation of pharmacogenetics in bipolar disorder., BMC Med
Rantamäki et al., 2006, The effects of acute and long-term lithium treatments on trkB neurotrophin receptor activation in the mouse hippocampus and anterior cingulate cortex., Neuropharmacology
Matayoshi et al., 2005, Actions of brain-derived neurotrophic factor on spinal nociceptive transmission during inflammation in the rat., J. Physiol. (Lond.)
Pearse et al., 2005, A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival., Blood
Joyce et al., 2004, Loss of D3 receptors in the zitter mutant rat is not reversed by L-dopa treatment., Exp. Neurol.
Middlemas et al., 1999, Brain derived neurotrophic factor protects human neuroblastoma cells from DNA damaging agents., J. Neurooncol.
Naert et al., 2006, Continuous i.c.v. infusion of brain-derived neurotrophic factor modifies hypothalamic-pituitary-adrenal axis activity, locomotor activity and body temperature rhythms in adult male rats., Neuroscience
Viviani et al., 2005, Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor., J. Neurochem.
Cargnin S et al., 2014, Combined effect of common gene variants on response to drug withdrawal therapy in medication overuse headache., Eur J Clin Pharmacol
Roy et al., 2007, Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin., J. Biol. Chem.
Wang et al., 2008, Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB., Brain Res.
Xu et al., 2007, Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats., Brain Res.
Nikolac Perkovic M et al., 2014, Association between the brain-derived neurotrophic factor Val66Met polymorphism and therapeutic response to olanzapine in schizophrenia patients., Psychopharmacology (Berl)
Perroud N et al., 2009, Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project., Neuropsychopharmacology
Duric et al., 2006, Effects of analgesic or antidepressant drugs on pain- or stress-evoked hippocampal and spinal neurokinin-1 receptor and brain-derived neurotrophic factor gene expression in the rat., J. Pharmacol. Exp. Ther.
Ramos et al., 2007, Diethylstilbestrol alters the population dynamic of neural precursor cells in the neonatal male rat dentate gyrus., Brain Res. Bull.
Faron-Górecka et al., 2004, Long-term exposure of rats to tramadol alters brain dopamine and alpha 1-adrenoceptor function that may be related to antidepressant potency., Eur. J. Pharmacol.
Ceccatelli et al., 1991, Expanded distribution of mRNA for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the rat brain after colchicine treatment., Proc. Natl. Acad. Sci. U.S.A.
Li et al., 2006, Repeated electroconvulsive stimuli increase brain-derived neurotrophic factor in ACTH-treated rats., Eur. J. Pharmacol.
Bozdagi et al., 2008, The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism., J. Neurosci.
Lochner et al., 2008, Efficient copackaging and cotransport yields postsynaptic colocalization of neuromodulators associated with synaptic plasticity., Dev Neurobiol
Kim et al., 2004, Continuous brain-derived neurotrophic factor (BDNF) infusion after methylprednisolone treatment in severe spinal cord injury., J. Korean Med. Sci.
Yagasaki et al., 2006, Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release., J. Biol. Chem.
Amino et al., 2002, Nerve growth factor enhances neurotransmitter release from PC12 cells by increasing Ca(2+)-responsible secretory vesicles through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase., J. Biochem.
Mizoguchi et al., 2006, BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons., Eur. J. Neurosci.
Van Hoomissen et al., 2003, Effects of chronic exercise and imipramine on mRNA for BDNF after olfactory bulbectomy in rat., Brain Res.
Millan et al., 2004, S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: III. Actions in models of potential antidepressive and anxiolytic activity in comparison with ropinirole., J. Pharmacol. Exp. Ther.
Yamanaka et al., 2007, Comparison of the antidiabetic effects of brain-derived neurotrophic factor and thiazolidinediones in obese diabetic mice., Diabetes Obes Metab
Serres et al., 2006, Nicotine regulates SH-SY5Y neuroblastoma cell proliferation through the release of brain-derived neurotrophic factor., Brain Res.
Pezet et al., 2002, BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn., Mol. Cell. Neurosci.
Hernández-Romero et al., 2008, Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide., J. Neurochem.
Van Hoomissen et al., 2004, Effects of beta-adrenoreceptor blockade during chronic exercise on contextual fear conditioning and mRNA for galanin and brain-derived neurotrophic factor., Behav. Neurosci.
Kawamoto et al., 1996, Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain., Neuroscience
Levran O et al., 2013, Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction., Pharmacogenomics
de Cid et al., 2008, BDNF variability in opioid addicts and response to methadone treatment: preliminary findings., Genes Brain Behav.
Zou YF et al., 2010, Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients., Neuropsychobiology
Ono et al., 1997, Brain-derived neurotrophic factor reduces blood glucose level in obese diabetic mice but not in normal mice., Biochem. Biophys. Res. Commun.
Ding et al., 2006, Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function., Neuroscience
Wang P et al., 2018, Association of DNA methylation in BDNF with escitalopram treatment response in depressed Chinese Han patients., Eur J Clin Pharmacol
Niitsu T et al., 2013, Pharmacogenetics in major depression: a comprehensive meta-analysis., Prog Neuropsychopharmacol Biol Psychiatry
Murphy GM Jr et al., 2013, BDNF and CREB1 genetic variants interact to affect antidepressant treatment outcomes in geriatric depression., Pharmacogenet Genomics
Musil R et al., 2013, No influence of brain-derived neurotrophic factor (BDNF) polymorphisms on treatment response in a naturalistic sample of patients with major depression., Eur Arch Psychiatry Clin Neurosci
Yoshimura R et al., 2011, The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients., Prog Neuropsychopharmacol Biol Psychiatry
Domschke K et al., 2010, Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response., Int J Neuropsychopharmacol
Hetman et al., 1999, Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase., J. Biol. Chem.
Mackin et al., 2007, Changes in brain-derived neurotrophic factor following treatment with mifepristone in bipolar disorder and schizophrenia., Aust N Z J Psychiatry
Iijima et al., 2005, Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA., Proc. Natl. Acad. Sci. U.S.A.
Mizoguchi et al., 2003, A rapid increase in the total number of cell surface functional GABAA receptors induced by brain-derived neurotrophic factor in rat visual cortex., J. Biol. Chem.
Zhu et al., 2007, Didanosine causes sensory neuropathy in an HIV/AIDS animal model: impaired mitochondrial and neurotrophic factor gene expression., Brain
Butovsky et al., 2005, In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol., J. Neurochem.
Ajmone-Cat et al., 2006, Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons., Neurobiol. Dis.
Wu et al., 2006, Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibroma., Am. J. Pathol.
Li et al., 2007, Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death., Cell Death Differ.
Poulsen et al., 2004, Differential expression of brain-derived neurotrophic factor transcripts after pilocarpine-induced seizure-like activity is related to mode of Ca2+ entry., Neuroscience
Wang et al., 2006, Secretion of brain-derived neurotrophic factor from PC12 cells in response to oxidative stress requires autocrine dopamine signaling., J. Neurochem.
Vaidya et al., 2001, Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression., Neuropharmacology
Leingärtner et al., 1994, Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons., J. Biol. Chem.
Pozzo-Miller, 2006, BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons., Brain Res.
Leyhe et al., 2008, Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease., Eur Arch Psychiatry Clin Neurosci
Chlan-Fourney et al., 2002, Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration., Brain Res.
Popper et al., 1999, Expression of BDNF and TrkB mRNAs in the crista neurosensory epithelium and vestibular ganglia following ototoxic damage., Brain Res.
Mustafa et al., 2008, 5-Fluorouracil chemotherapy affects spatial working memory and newborn neurons in the adult rat hippocampus., Eur. J. Neurosci.

K-252A BDNF

Interaction Score: 0.97

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16797499

Sources:
NCI
VERTEPORFIN BDNF

Interaction Score: 0.97

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15505074

Sources:
NCI
NYSTATIN BDNF

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12941963

Sources:
NCI
THYROGLOBULIN BDNF

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8895887

Sources:
NCI
FLURBIPROFEN BDNF

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16531049

Sources:
NCI
PAROXETINE BDNF

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29748862 23733030 23619509 22965830 21338649 20016225 19236730

Sources:
PharmGKB
DIACETYLMORPHINE BDNF

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28692418 26401760 24279859

Sources:
PharmGKB
DONEPEZIL BDNF

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17990049

Sources:
NCI
DRONABINOL BDNF

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15857384

Sources:
NCI
CITALOPRAM BDNF

Interaction Score: 0.23

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29748862 23733030 23619509 22965830 21338649 20016225 19236730

Sources:
PharmGKB
GLUCAGON BDNF

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17924870

Sources:
NCI
IONOMYCIN BDNF

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12038986

Sources:
NCI
CORTICOTROPIN BDNF

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16330021

Sources:
NCI
BACLOFEN BDNF

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17074039

Sources:
NCI
GEMFIBROZIL BDNF

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17823123

Sources:
NCI
METYROSINE BDNF

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16390493

Sources:
NCI
NALOXONE BDNF

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12359151

Sources:
NCI
IMIPRAMINE BDNF

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16522641

Sources:
NCI
NORTRIPTYLINE BDNF

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19641488

Sources:
PharmGKB
DIDANOSINE BDNF

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17616550

Sources:
NCI
ALTEPLASE BDNF

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18815270 18563704

Sources:
NCI
PILOCARPINE BDNF

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15183516

Sources:
NCI
METHAMPHETAMINE BDNF

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28692418 26401760 24279859

Sources:
PharmGKB
INOSITOL BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16286649

Sources:
NCI
METHADONE BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23651024 18182069

Sources:
NCI PharmGKB
SODIUM CHLORIDE BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12742641

Sources:
NCI
SUMATRIPTAN BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25096645

Sources:
PharmGKB
EPOETIN BETA BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15816864

Sources:
NCI
NICARDIPINE BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10748141

Sources:
NCI
VENLAFAXINE BDNF

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14978196

Sources:
NCI
METHYLPREDNISOLONE BDNF

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14966352

Sources:
NCI
TOPOTECAN BDNF

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15569250

Sources:
NCI
CAPSAICIN BDNF

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10430952

Sources:
NCI
PROPRANOLOL BDNF

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15598146

Sources:
NCI
VASOPRESSIN BDNF

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16457953

Sources:
NCI
LIDOCAINE BDNF

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16210356

Sources:
NCI
PROPYLTHIOURACIL BDNF

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11077070

Sources:
NCI
TRAMADOL BDNF

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15464068

Sources:
NCI
ESCITALOPRAM BDNF

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19641488

Sources:
PharmGKB
MIFEPRISTONE BDNF

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17464718

Sources:
NCI
GENTAMICIN BDNF

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10536212

Sources:
NCI
CHLORPROMAZINE BDNF

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18408624

Sources:
NCI
LITHIUM BDNF

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24885933 16300803

Sources:
NCI PharmGKB
TROGLITAZONE BDNF

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17924870

Sources:
NCI
FLUOXETINE BDNF

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20016225

Sources:
PharmGKB
DIETHYLSTILBESTROL BDNF

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17292805

Sources:
NCI
DESIPRAMINE BDNF

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
LIOTHYRONINE SODIUM BDNF

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8288635

Sources:
NCI
INSULIN BDNF

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9299565 16650607

Sources:
NCI
INDOMETHACIN BDNF

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16956981

Sources:
NCI
CAMPTOTHECIN BDNF

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10428835

Sources:
NCI
LEVODOPA BDNF

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15081599

Sources:
NCI
CETUXIMAB BDNF

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16651634

Sources:
NCI
COLCHICINE BDNF

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1946455

Sources:
NCI
CURCUMIN BDNF

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18420184 17617388

Sources:
NCI
NICOTINE BDNF

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16790237

Sources:
NCI
SIMVASTATIN BDNF

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18047562

Sources:
NCI
VINCRISTINE BDNF

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15569250

Sources:
NCI
HALOPERIDOL BDNF

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12393228

Sources:
NCI
OLANZAPINE BDNF

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24595507

Sources:
PharmGKB
BORTEZOMIB BDNF

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15657181

Sources:
NCI
DOXORUBICIN BDNF

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10728907

Sources:
NCI
PACLITAXEL BDNF

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16778834

Sources:
NCI
FLUOROURACIL BDNF

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18702703

Sources:
NCI

Ensembl: ENSG00000176697
- Version: 101_38
Alternate Names:

BDNF Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: BDNF

Version: 18-August-2020

Alternate Names:

PA31891 PharmGKB ID

Gene Info:

Publications:

Haerian BS, 2013, BDNF rs6265 polymorphism and drug addiction: a systematic review and meta-analysis., Pharmacogenomics

Gao X et al., 2017, Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese., OMICS

Iamjan SA et al., 2015, BDNF (Val66Met) genetic polymorphism is associated with vulnerability for methamphetamine dependence., Pharmacogenomics

NCI: BDNF

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Mannion et al., 1999, Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity., Proc. Natl. Acad. Sci. U.S.A.

Xu et al., 2008, BDNF gene is a genetic risk factor for schizophrenia and is related to the chlorpromazine-induced extrapyramidal syndrome in the Chinese population., Pharmacogenet. Genomics

Tabuchi et al., 2000, Differential activation of brain-derived neurotrophic factor gene promoters I and III by Ca2+ signals evoked via L-type voltage-dependent and N-methyl-D-aspartate receptor Ca2+ channels., J. Biol. Chem.

HingoraniCasas: ENSG00000176697
- Version: 31-May-2017
Alternate Names:

ENSG00000176697 Gene Symbol

BDNF Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
TTD: Brain-derived neurotrophic factor
- Version: 2020.06.01
Alternate Names:

BDNF TTD Gene Abbreviation

T93122 TTD Target ID

Gene Info:

Publications:
GO: BDNF
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

GROWTH FACTOR

Publications:

BDNF Gene Record

BDNF 627 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16797499

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15505074

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12941963

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8895887

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16531049

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 29748862 23733030 23619509 22965830 21338649 20016225 19236730

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 28692418 26401760 24279859

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17990049

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15857384

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 29748862 23733030 23619509 22965830 21338649 20016225 19236730

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17924870

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12038986

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16330021

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17074039

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17823123

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16390493

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12359151

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16522641

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

n/a

PMIDs:
16797499

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15505074

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
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Sources:
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Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
PharmGKB

Interaction Types & Directionality:

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PMIDs:
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Sources:
PharmGKB

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
PharmGKB

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
PharmGKB

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
NCI

Interaction Types & Directionality:

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PMIDs:
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Sources:
PharmGKB

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Sources:
NCI

Interaction Types & Directionality:

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Interaction Types & Directionality:

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Sources:
NCI

Interaction Types & Directionality:

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