• CA9 768 Druggable GenomeDrug Resistance

    Alternate Names:

    768
    CARBONIC ANHYDRASE 9
    CA9
    CAIX
    MN
    603179
    1383
    ENSG00000107159
    OTTHUMG00000021029
    CARBONIC ANHYDRASE IX PRECURSOR (EC 4.2.1.1) (CARBONATE DEHYDRATASE IX) (CA-IX) (CAIX) (MEMBRANE ANTIGEN MN) (P54/58N) (RENAL CELL CARCINOMA-ASSOCIATED ANTIGEN G250) (RCC-ASSOCIATED ANTIGEN G250) (PMW1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q16790]
    Q16790
    CAH9_HUMAN
    RCC-associated antigen G250
    CA-IX
    pMW1
    Renal cell carcinoma-associated antigen G250
    P54/58N
    Membrane antigen MN
    Carbonic anhydrase IX
    Carbonate dehydratase IX
    G250
    PA25998
    T64567
    NP_001207
    NM_139305
    3055

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Carbonic_anhydrase_a
    Interpro Name Alpha carbonic anhydrase
    Interpro Type Domain
    Interpro Acc IPR001148
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Carbonic anhydrases
    GuideToPharmacology Gene Category ID 842
    (6 More Sources)

    Gene Categories: Category Details

    DRUG RESISTANCE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 5.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Carbonic anhydrase IX binding agent
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Carbonic anhydrase IX binding agent
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Carbonic anhydrase IX binding agent

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Carbonic anhydrase IX other
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.41

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Carbonic anhydrase inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Alteration CA9:over
    Drug family Pan-TK inhibitor

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

    • Version: 101_38

    Alternate Names:
    CA9 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000107159 Ensembl Gene Id
    CA9 Display Id
    CARBONIC ANHYDRASE IX PRECURSOR (EC 4.2.1.1) (CARBONATE DEHYDRATASE IX) (CA-IX) (CAIX) (MEMBRANE ANTIGEN MN) (P54/58N) (RENAL CELL CARCINOMA-ASSOCIATED ANTIGEN G250) (RCC-ASSOCIATED ANTIGEN G250) (PMW1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q16790] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    CARBONIC ANHYDRASE 9 Uniprot Protein Name
    CA9 Uniprot Gene Name
    CAH9_HUMAN Uniprot Id

    Gene Info:
    Interpro Short Name Carbonic_anhydrase_a
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Alpha carbonic anhydrase

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1383 HUGO Gene ID
    1383 HUGO Gene Symbol
    carbonic anhydrase 9 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Carbonic anhydrases
    GuideToPharmacology Gene Category ID 842

    Gene Categories:
    ENZYME

    Publications:

    • Version: 18-August-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000107159 Gene Symbol
    CA9 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    MN GENE_SYMBOL
    CA9 GENE_SYMBOL
    Carbonic anhydrase 9 UNIPROT

    Gene Info:

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    CA-IX TTD Gene Abbreviation
    T64567 TTD Target ID

    Gene Info:

    Publications:

  • GO: CA9

    • Version: 01-May-2021

    Alternate Names:
    G250 GO Gene Synonym
    MN GO Gene Synonym

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:

  • CGI: CA9

    • Version: 27-September-2017

    Alternate Names:

    Gene Info:

    Publications: