• CACNA1E 777 Druggable Genome

    Alternate Names:

    777
    CALCIUM VOLTAGE-GATED CHANNEL SUBUNIT ALPHA1 E
    CACNA1E
    BII
    CACH6
    CACNL1A6
    Cav2.3
    gm139
    601013
    1392
    ENSG00000198216
    OTTHUMG00000037301
    Voltage-gated calcium channel subunit alpha Cav2.3
    Calcium channel, L type, alpha-1 polypeptide, isoform 6
    Brain calcium channel II
    Voltage-dependent R-type calcium channel subunit alpha-1E
    PA26009
    CAC1E_HUMAN
    Q15878
    534
    Ca<sub>v</sub>2.3
    NM_000721
    NP_000712
    VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL ALPHA-1E SUBUNIT (VOLTAGE- GATED CALCIUM CHANNEL ALPHA SUBUNIT CAV2.3) (CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 6) (BRAIN CALCIUM CHANNEL II) (BII). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15878]
    DEE69
    EIEE69

    Gene Info:

    Initial Gene Query Cav2.3
    Counted Citations from 1950-2000 334
    GuideToPharmacology Gene Category Name Voltage-gated calcium channels
    GuideToPharmacology Gene Category ID 80
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name ION CHANNEL
    Uniprot Status Swiss-Prot
    Interpro Short Name Ion_trans_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR005821
    Interpro Name Ion transport domain
    Interpro Type Domain
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 0.32

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.32

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


  • Interaction Score: 0.32

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.32

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.32

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Interaction Score: 0.27

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

    • Version: 101_38

    Alternate Names:
    CACNA1E Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    777 Entrez Gene ID

    Gene Info:
    Initial Gene Query Cav2.3
    Counted Citations from 1950-2000 334

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000198216 Ensembl Gene Id
    VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL ALPHA-1E SUBUNIT (VOLTAGE- GATED CALCIUM CHANNEL ALPHA SUBUNIT CAV2.3) (CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 6) (BRAIN CALCIUM CHANNEL II) (BII). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15878] Description
    CACNA1E Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    777 Entrez Gene Id
    CAC1E_HUMAN Uniprot Id
    CACNA1E Uniprot Gene Name

    Gene Info:
    Human Readable Name ION CHANNEL
    Uniprot Status Swiss-Prot
    Interpro Short Name Ion_trans_dom

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1392 HUGO Gene ID
    1392 HUGO Gene Symbol
    calcium voltage-gated channel subunit alpha1 E HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Voltage-gated calcium channels
    GuideToPharmacology Gene Category ID 80

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 18-August-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000198216 Gene Symbol
    CACNA1E Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    CACNL1A6 GENE_SYMBOL
    CACNA1E GENE_SYMBOL
    Voltage-dependent R-type calcium channel subunit alpha-1E UNIPROT

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Voltage-dependent R-type calcium channel subunit alpha-1E Gene Name
    Q15878 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: