• Interaction Score: 2.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 2.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 2.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

  • Interaction Score: 1.52

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Pore blocker
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 1.34

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

  • Interaction Score: 1.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 1.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name zonisamide,Zonegran, Trerief
    Trial Name OREX-003, olanzapine plus zonisamide SR
    Novel drug target Established target

  • Interaction Score: 0.76

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated T-type calcium channel blocker

    PMIDs:
    None found


  • Interaction Score: 0.76

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated T-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.76

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated T-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.57

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated T-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.46

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated T-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.33

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated T-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.14

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? True

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    CACNA1H Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    CAC1H_HUMAN Uniprot Id
    VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1H Uniprot Protein Name
    CACNA1H Uniprot Gene Name

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Name Ion transport domain
    Interpro Acc IPR005821

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: February-2014

    Alternate Names:
    8912 Entrez Gene ID

    Gene Info:
    Initial Gene Query Cav3.2
    Counted Citations from 1950-2000 349

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL ALPHA-1H SUBUNIT (VOLTAGE- GATED CALCIUM CHANNEL ALPHA SUBUNIT CAV3.2) (LOW-VOLTAGE-ACTIVATED CALCIUM CHANNEL ALPHA1 3.2 SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:O95180] Description
    ENSG00000196557 Ensembl Gene Id
    CACNA1H Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    8912 Entrez Gene Id
    CAC1H_HUMAN Uniprot Id
    O95180 Uniprot Accession

    Gene Info:
    Target Subclass Channels
    Target Main Class Transporters
    Target Subclass Voltage_gated_ion_channels

    Publications:

    • Version: January-2014

    Alternate Names:
    CACNA1H Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:1.A.1.11.5

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1395 HUGO Gene ID
    1395 HUGO Gene Symbol
    calcium voltage-gated channel subunit alpha1 H HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Voltage-gated calcium channels
    GuideToPharmacology Gene Category ID 80

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 18-August-2020
    • Version: chembl_23

    Alternate Names:
    CACNA1H GENE_SYMBOL
    Voltage-dependent T-type calcium channel subunit alpha-1H UNIPROT
    Low-voltage-activated calcium channel alpha1 3.2 subunit UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000196557 Gene Symbol
    CACNA1H Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Alternate Names:
    CACNA1H TTD Gene Abbreviation
    T54644 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Voltage-dependent T-type calcium channel subunit alpha-1H Gene Name
    O95180 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: