-
CASP1 834 Druggable Genome
Alternate Names:
834 CASPASE 1 CASP1 ICE IL1BC P45 147678 1499 ENSG00000137752 OTTHUMG00000048072 P29466 CASPASE-1 SUBUNIT P20 CASP1_HUMAN IL1BCE CASPASE-1 PRECURSOR (EC 3.4.22.36) (CASP-1) (INTERLEUKIN-1 BETA CONVERTASE) (IL-1BC) (IL-1 BETA CONVERTING ENZYME) (ICE) (INTERLEUKIN- 1 BETA CONVERTING ENZYME) (P45). [SOURCE:UNIPROT/SWISSPROT;ACC:P29466] IL-1 beta-converting enzyme IL-1BC CASP-1 Interleukin-1 beta-converting enzyme Interleukin-1 beta convertase Caspase-1 subunit p10 Caspase-1 T98269 Gene Info:
Human Readable Name PROTEASE Interpro Acc IPR002398 Interpro Name Peptidase C14, caspase precursor p45 Uniprot Evidence 1: Evidence at protein level Interpro Short Name Pept_C14_p45 Uniprot Status Swiss-Prot Interpro Type Family Human Readable Name DRUGGABLE GENOME Target Class Enzymes Target Subclass EC:3.4.22.36 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
PROTEASE DRUGGABLE GENOME ENZYME Publications:
-
Interaction Score: 5.38
-
Interaction Score: 5.38
-
Interaction Score: 5.38
-
Interaction Score: 5.38
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name VX-765 Novel drug target Novel Target -
Interaction Score: 2.69
-
Interaction Score: 2.69
-
Interaction Score: 2.69
-
Interaction Score: 2.69
-
Interaction Score: 2.69
-
Interaction Score: 2.69
-
Interaction Score: 2.69
-
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Caspase-1 inhibitor Direct Interaction yes -
Interaction Score: 0.45
-
Interaction Score: 0.38
-
Interaction Score: 0.24
-
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Caspase inhibitor Direct Interaction yes -
Interaction Score: 0.13
-
Interaction Score: 0.1
-
Interaction Score: 0.09
-
Interaction Score: 0.05
-
- Version: 101_38
Alternate Names:
CASP1 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
- Version: 26-July-2011
Alternate Names:
ENSG00000137752 Ensembl Gene Id CASPASE-1 PRECURSOR (EC 3.4.22.36) (CASP-1) (INTERLEUKIN-1 BETA CONVERTASE) (IL-1BC) (IL-1 BETA CONVERTING ENZYME) (ICE) (INTERLEUKIN- 1 BETA CONVERTING ENZYME) (P45). [SOURCE:UNIPROT/SWISSPROT;ACC:P29466] Description CASP1 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: January-2014
Alternate Names:
CASP1 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:3.4.22.36 Publications:
-
- Version: 11-September-2012
Alternate Names:
834 Entrez Gene Id CASP1 Uniprot Gene Name CASP1_HUMAN Uniprot Id Gene Info:
Interpro Acc IPR002398 Interpro Name Peptidase C14, caspase precursor p45 Uniprot Evidence 1: Evidence at protein level Gene Categories:
PROTEASE, DRUGGABLE GENOME Publications:
-
Alternate Names:
Gene Info:
Publications:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000137752 Gene Symbol CASP1 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: chembl_23
Alternate Names:
IL1BCE GENE_SYMBOL CASP1 GENE_SYMBOL Caspase-1 UNIPROT Gene Info:
Publications:
-
Alternate Names:
834 Gene ID ICE dGene Synonym IL1BC dGene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
-
Alternate Names:
CASP1 TTD Gene Abbreviation T98269 TTD Target ID Gene Info:
Publications:
-
Alternate Names:
Caspase-1 Gene Name P29466 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: