• CASP4 837 Druggable Genome

    Alternate Names:

    837
    CASPASE 4
    CASP4
    ICE(rel)II
    ICEREL-II
    ICH-2
    Mih1
    Mih1/TX
    TX
    602664
    1505
    ENSG00000196954
    OTTHUMG00000166078
    ICH2
    Caspase-4 subunit 2
    Caspase-4
    CASP-4
    Protease TX
    ICE(rel)-II
    ICE and Ced-3 homolog 2
    Caspase-4 subunit 1
    CASP4_HUMAN
    P49662
    1620
    NP_001216|NP_150649
    NM_001225|NM_033306
    CASPASE-4 PRECURSOR (EC 3.4.22.-) (CASP-4) (ICH-2 PROTEASE) (TX PROTEASE) (ICE(REL)-II). [SOURCE:UNIPROT/SWISSPROT;ACC:P49662]
    BE0009964

    Gene Info:

    Human Readable Name PROTEASE
    GuideToPharmacology Gene Category Name C14: Caspase
    GuideToPharmacology Gene Category ID 734
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002398
    Interpro Name Peptidase C14, caspase precursor p45
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Pept_C14_p45
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 14.2

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:

    PMIDs:
    23044853


    Sources:
    DrugBank

  • Interaction Score: 2.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Caspase inhibitor

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    CASP4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    CASPASE-4 PRECURSOR (EC 3.4.22.-) (CASP-4) (ICH-2 PROTEASE) (TX PROTEASE) (ICE(REL)-II). [SOURCE:UNIPROT/SWISSPROT;ACC:P49662] Description
    CASP4 Display Id
    ENSG00000196954 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    CASP4 Uniprot Gene Name
    CASPASE-4 Uniprot Protein Name
    P49662 Uniprot Accession

    Gene Info:
    Interpro Type Family
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002398

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1505 HUGO Gene ID
    1505 HUGO Gene Symbol
    caspase 4 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name C14: Caspase
    GuideToPharmacology Gene Category ID 734

    Gene Categories:
    ENZYME

    Publications:

    • Version: 5.1.7

    Alternate Names:
    CASP4 DrugBank Gene Name
    P49662 UniProt Accession
    837 Entrez Gene Id

    Gene Info:

    • Version: chembl_23

    Alternate Names:
    ICH2 GENE_SYMBOL
    CASP4 GENE_SYMBOL
    Caspase-4 UNIPROT

    Gene Info:

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Caspase-4 Gene Name
    P49662 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    837 Gene ID
    ICE(rel)II dGene Synonym
    ICEREL-II dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications: