• CASP8 841 Druggable GenomeClinically Actionable

    Alternate Names:

    841
    CASPASE 8
    CASP8
    ALPS2B
    CAP4
    Casp-8
    FLICE
    MACH
    MCH5
    601763
    1509
    ENSG00000064012
    OTTHUMG00000132821
    Apoptotic cysteine protease
    Apoptotic protease Mch-5
    Caspase-8 subunit p10
    Caspase-8 subunit p18
    FADD-homologous ICE/ced-3-like protease
    Caspase-8
    FADD-like ICE
    ICE-like apoptotic protease 5
    MORT1-associated ced-3 homolog
    CASPASE-8 PRECURSOR (EC 3.4.22.-) (CASP-8) (ICE-LIKE APOPTOTIC PROTEASE 5) (MORT1-ASSOCIATED CED-3 HOMOLOG) (MACH) (FADD-HOMOLOGOUS ICE/CED-3-LIKE PROTEASE) (FADD-LIKE ICE) (FLICE) (APOPTOTIC CYSTEINE PROTEASE) (APOPTOTIC PROTEASE MCH-5) (CAP4). [SOURCE:U
    1624
    Q14790
    CASP8_HUMAN
    761
    caspase 8, apoptosis-related cysteine peptidase
    NM_001080124|NM_001080125|NM_001228|NM_033355|NM_033356|NM_033358
    NP_001073593|NP_001073594|NP_001219|NP_203519|NP_203520|NP_203522
    T15700
    BE0003460

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Human Readable Name PROTEASE
    Interpro Short Name Pept_C14_p45
    Interpro Acc IPR002398
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Name Peptidase C14, caspase precursor p45
    GuideToPharmacology Gene Category Name C14: Caspase
    GuideToPharmacology Gene Category ID 734
    GuideToPharmacology Gene Type enzyme
    Gene Biotype PROTEIN_CODING
    (14 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME
    • Version: 101_38

    Alternate Names:
    CASP8 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    caspase 8, apoptosis-related cysteine peptidase HUGO Gene Name
    1509 HUGO Gene ID
    CASP8 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name C14: Caspase
    GuideToPharmacology Gene Category ID 734
    GuideToPharmacology Gene Type enzyme

    Gene Categories:
    PROTEASE

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    Q14790 Uniprot Accession
    CASP8_HUMAN Uniprot Id
    CASP8 Uniprot Gene Name

    Gene Info:
    Interpro Short Name Pept_C14_p45
    Interpro Acc IPR002398
    Interpro Type Family

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    CASPASE-8 PRECURSOR (EC 3.4.22.-) (CASP-8) (ICE-LIKE APOPTOTIC PROTEASE 5) (MORT1-ASSOCIATED CED-3 HOMOLOG) (MACH) (FADD-HOMOLOGOUS ICE/CED-3-LIKE PROTEASE) (FADD-LIKE ICE) (FLICE) (APOPTOTIC CYSTEINE PROTEASE) (APOPTOTIC PROTEASE MCH-5) (CAP4). [SOURCE:U Description
    ENSG00000064012 Ensembl Gene Id
    CASP8 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 5.1.7

    Alternate Names:
    CASP8 DrugBank Gene Name
    Q14790 UniProt Accession
    841 Entrez Gene Id

    Gene Info:

    • Version: 02-September-2020
    • Version: chembl_23

    Alternate Names:
    MCH5 GENE_SYMBOL
    CASP8 GENE_SYMBOL
    Caspase-8 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000064012 Gene Symbol
    CASP8 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Alternate Names:
    Caspase 8 GuideToPharmacology Name
    Q14790 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    CASP8 TTD Gene Abbreviation
    T15700 TTD Target ID

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000064012 Ensembl Gene ID
    Casp-8 Human Protein Atlas Gene Synonym
    FLICE Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Caspase-8 Gene Name
    Q14790 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    MCH5 GO Gene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

    • Version: 11-November-2018

    Alternate Names:
    CASP8 Gene Symbol

    Gene Info:

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    841 Gene ID
    ALPS2B dGene Synonym
    CAP4 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: