• Interaction Score: 9.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction T cell surface glycoprotein CD3 inhibitor

  • Interaction Score: 6.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name NI-0401
    Novel drug target Established target
    Mechanism of Interaction T cell surface glycoprotein CD3 inhibitor

    PMIDs:
    None found


  • Interaction Score: 3.91

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction T cell surface glycoprotein CD3 cross-linking agent
    Trial Name MT-103

  • Interaction Score: 3.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Nuvion
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 3.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name otelixizumab, TRX4, GSK2136525
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 2.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name MT110
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 2.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name catumaxomab,Removab
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

    • Version: 101_38

    Alternate Names:
    CD3D Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    CD3D Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptor
    Target Subclass T-cell receptor subunit

    Publications:

    • Version: chembl_23

    Alternate Names:
    T3D GENE_SYMBOL
    CD3D GENE_SYMBOL
    T-cell surface glycoprotein CD3 delta chain UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000167286 Gene Symbol
    CD3D Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: CD3D

    • Version: 01-May-2021

    Alternate Names:
    T3D GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    T-cell surface glycoprotein CD3 delta chain Gene Name
    P04234 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: