• CDC7 8317 Druggable Genome

    Alternate Names:

    8317
    CELL DIVISION CYCLE 7
    CDC7
    CDC7L1
    HsCDC7
    Hsk1
    huCDC7
    603311
    1745
    ENSG00000097046
    OTTHUMG00000047810
    O00311
    CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE (EC 2.7.1.-) (CDC7- RELATED KINASE) (HSCDC7) (HUCDC7). [SOURCE:UNIPROT/SWISSPROT;ACC:O00311]
    1960
    NP_001127891
    NM_001134419
    CDC7-related kinase
    Cell division cycle 7-related protein kinase
    T81358

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Target Class Enzymes
    Target Subclass EC:2.7.11.1
    GuideToPharmacology Gene Category Name CDC7 family
    GuideToPharmacology Gene Category ID 567
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 13.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name BMS-863233, XL-413
    Novel drug target Novel Target
    Mechanism of Interaction Cell division cycle 7-related protein kinase inhibitor

    PMIDs:
    None found


  • Interaction Score: 8.74

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Details of Interaction Inhibits CDC7/Dbf4 complex activity by 103 % in a proprietary HTRF ADP formation assay (Transcreener, Cisbio)
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 8.74

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Cell division cycle 7-related protein kinase inhibitor
    Direct Interaction yes
    Novel drug target Novel Target

    PMIDs:
    None found


  • Interaction Score: 4.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Cell division cycle 7-related protein kinase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18469809


    Sources:
    DTC

  • Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    CDC7 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    CDC7 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.1

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000097046 Ensembl Gene Id
    CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE (EC 2.7.1.-) (CDC7- RELATED KINASE) (HSCDC7) (HUCDC7). [SOURCE:UNIPROT/SWISSPROT;ACC:O00311] Description
    CDC7 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1745 HUGO Gene ID
    1745 HUGO Gene Symbol
    cell division cycle 7 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name CDC7 family
    GuideToPharmacology Gene Category ID 567

    Gene Categories:
    ENZYME

    Publications:

    • Version: 02-September-2020
    • Version: chembl_23

    Alternate Names:
    CDC7L1 GENE_SYMBOL
    CDC7 GENE_SYMBOL
    Cell division cycle 7-related protein kinase UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000097046 Gene Symbol
    CDC7 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Cell division cycle 7-related protein kinase Gene Name
    O00311 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: CDC7

    • Version: 05-September-2020

    Alternate Names:
    CDC7L1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    8317 Gene ID
    CDC7L1 dGene Synonym
    HsCDC7 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    CDC7 TTD Gene Abbreviation
    T81358 TTD Target ID

    Gene Info:

    Publications: