• CHRNA6 8973 Druggable Genome

    Alternate Names:

    8973
    CHOLINERGIC RECEPTOR NICOTINIC ALPHA 6 SUBUNIT
    CHRNA6
    CHNRA6
    606888
    15963
    ENSG00000147434
    OTTHUMG00000165275
    ACHA6_HUMAN
    Q15825
    467
    nicotinic acetylcholine receptor α6 subunit
    Neuronal acetylcholine receptor subunit alpha-6
    NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-6 SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:Q15825]
    NM_004198
    NP_004189

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR006201
    Interpro Type Domain
    Interpro Short Name Neur_channel
    Interpro Name Neurotransmitter-gated ion-channel
    Uniprot Status Swiss-Prot
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Neur_chan_lig-bd
    Human Readable Name ION CHANNEL
    Interpro Acc IPR006202
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Nicotinic acetylcholine receptors
    GuideToPharmacology Gene Category ID 76
    (3 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 5.32

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Mechanism of Interaction Neuronal acetylcholine receptor; alpha6/beta2 partial agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction α6/α3β2β3 chimera
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 2.13

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction α6/α3β2β3 chimera
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    CHRNA6 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    8973 Entrez Gene Id
    Q15825 Uniprot Accession
    ENSG00000147434 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR006201
    Interpro Type Domain

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-6 SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:Q15825] Description
    CHRNA6 Display Id
    ENSG00000147434 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    15963 HUGO Gene ID
    15963 HUGO Gene Symbol
    cholinergic receptor nicotinic alpha 6 subunit HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Nicotinic acetylcholine receptors
    GuideToPharmacology Gene Category ID 76

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: chembl_23

    Alternate Names:
    CHRNA6 GENE_SYMBOL
    Neuronal acetylcholine receptor subunit alpha-6 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000147434 Gene Symbol
    CHRNA6 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Neuronal acetylcholine receptor subunit alpha-6 Gene Name
    Q15825 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: