• Interaction Score: 5.32

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Details of Interaction α9α10
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 2.28

    Interaction Types & Directionality:
    agonist (activating)
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Specific Action of the Ligand Antagonist

  • Interaction Score: 1.77

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Neuronal acetylcholine receptor; alpha9/alpha10 antagonist

    PMIDs:
    None found


  • Interaction Score: 1.59

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Details of Interaction (&alpha;9)<sub>5</sub>
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    CHRNA9 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-9 SUBUNIT PRECURSOR (NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA 9) (NACHR ALPHA 9). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UGM1] Description
    CHRNA9 Display Id
    ENSG00000174343 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 Uniprot Protein Name
    CHRNA9 Uniprot Gene Name
    ACHA9_HUMAN Uniprot Id

    Gene Info:
    Interpro Type Domain
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Acc IPR006201

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    ACHA9_HUMAN Uniprot Id
    Q9UGM1 Uniprot Accession
    ENSG00000174343 Ensembl Gene Id

    Gene Info:
    Target Subclass Channels
    Target Main Class Receptors
    Target Subclass Ligand_gated_ion_channels

    Publications:

    • Version: January-2014

    Alternate Names:
    CHRNA9 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass TC:1.A.9

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    14079 HUGO Gene ID
    14079 HUGO Gene Symbol
    cholinergic receptor nicotinic alpha 9 subunit HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Nicotinic acetylcholine receptors
    GuideToPharmacology Gene Category ID 76

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: chembl_23

    Alternate Names:
    NACHRA9 GENE_SYMBOL
    CHRNA9 GENE_SYMBOL
    Neuronal acetylcholine receptor subunit alpha-9 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000174343 Gene Symbol
    CHRNA9 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Neuronal acetylcholine receptor subunit alpha-9 Gene Name
    Q9UGM1 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: