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CHUK 1147 Druggable GenomeDrug Resistance
Alternate Names:
1147 CONSERVED HELIX-LOOP-HELIX UBIQUITOUS KINASE CHUK IKBKA IKK-alpha IKK1 IKKA NFKBIKA TCF16 600664 1974 ENSG00000213341 OTTHUMG00000018899 O15111 1989 NP_001269 NM_001278 BE0004655 IKKA_HUMAN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT ALPHA ENSG00000107566 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE ALPHA SUBUNIT (EC 2.7.1.-) (I KAPPA-B KINASE ALPHA) (IKBKA) (IKK-ALPHA) (IKK-A) (IKAPPAB KINASE) (I-KAPPA-B KINASE 1) (IKK1) (CONSERVED HELIX-LOOP-HELIX UBIQUITOUS KINASE) (NUCLEAR FACTOR NFKAPPAB INHIBITOR KINAS component of inhibitor of nuclear factor kappa B kinase complex Gene Info:
Target Class Enzymes Target Subclass EC:2.7.11.10 GuideToPharmacology Gene Category Name IKK family GuideToPharmacology Gene Category ID 578 Interpro Acc IPR002290 Uniprot Evidence 1: Evidence at protein level Interpro Short Name Ser/Thr_dual-sp_kinase_dom Human Readable Name DRUGGABLE GENOME Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain Human Readable Name KINASE Interpro Type Domain Uniprot Status Swiss-Prot Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE SERINE THREONINE KINASE DRUG RESISTANCE DRUGGABLE GENOME ENZYME TRANSCRIPTION FACTOR Publications:
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Interaction Score: 9.47
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Interaction Score: 9.47
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Interaction Score: 9.47
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Interaction Score: 9.47
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Interaction Score: 4.73
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Interaction Score: 2.37
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Score: 1.58
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Interaction Score: 1.13
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name SPD476,Lialda Novel drug target Established target -
Interaction Score: 0.49
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Interaction Score: 0.47
Interaction Types & Directionality:
allosteric modulator Interaction Info:
Specific Action of the Ligand Negative Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.38
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Interaction Score: 0.17
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- Version: 101_38
Alternate Names:
CHUK Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
ENSG00000213341 Ensembl Gene Id IKKA_HUMAN Uniprot Id CHUK Uniprot Gene Name Gene Info:
Interpro Acc IPR002290 Uniprot Evidence 1: Evidence at protein level Interpro Short Name Ser/Thr_dual-sp_kinase_dom Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
CHUK Display Id INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE ALPHA SUBUNIT (EC 2.7.1.-) (I KAPPA-B KINASE ALPHA) (IKBKA) (IKK-ALPHA) (IKK-A) (IKAPPAB KINASE) (I-KAPPA-B KINASE 1) (IKK1) (CONSERVED HELIX-LOOP-HELIX UBIQUITOUS KINASE) (NUCLEAR FACTOR NFKAPPAB INHIBITOR KINAS Description ENSG00000107566 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
CHUK Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:2.7.11.10 Publications:
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- Version: 29-September-2020
Alternate Names:
1974 HUGO Gene ID 1974 HUGO Gene Symbol component of inhibitor of nuclear factor kappa B kinase complex HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name IKK family GuideToPharmacology Gene Category ID 578 Gene Categories:
ENZYME Publications:
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Alternate Names:
CHUK DrugBank Gene Name O15111 UniProt Accession 1147 Entrez Gene Id Gene Info:
Publications:
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Alternate Names:
Gene Info:
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Alternate Names:
Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000213341 Gene Symbol CHUK Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 19.3
Alternate Names:
ENSG00000213341 Ensembl Gene ID IkBKA Human Protein Atlas Gene Synonym IKK-alpha Human Protein Atlas Gene Synonym Gene Info:
Gene Categories:
ENZYME Publications:
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Alternate Names:
Inhibitor of nuclear factor kappa-B kinase subunit alpha Gene Name O15111 UniProt ID Gene Info:
Gene Categories:
KINASE, TRANSCRIPTION FACTOR Publications:
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Alternate Names:
IKKA GO Gene Synonym TCF16 GO Gene Synonym Gene Info:
Gene Categories:
SERINE THREONINE KINASE, DRUG RESISTANCE Publications:
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Alternate Names:
1147 Gene ID IKBKA dGene Synonym IKK-alpha dGene Synonym Gene Info:
Gene Categories:
KINASE, SERINE THREONINE KINASE Publications: