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CREB1 Gene Record

  • Summary
  • Interactions
  • Claims
  • CREB1 1385 Clinically Actionable

    Alternate Names:

    1385
    CAMP RESPONSIVE ELEMENT BINDING PROTEIN 1
    CREB1
    CREB
    CREB-1
    123810
    2345
    ENSG00000118260
    OTTHUMG00000132936
    PA26864
    Cyclic AMP-responsive element-binding protein 1
    P16220

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    TRANSCRIPTION FACTOR COMPLEX
    KINASE
    CLINICALLY ACTIONABLE
    TRANSCRIPTION FACTOR

    Publications:

    Serretti A et al., 2011, A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression., J Affect Disord
    Perlis RH et al., 2007, Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study., Arch Gen Psychiatry
    Salloum NC et al., 2014, Towards the clinical implementation of pharmacogenetics in bipolar disorder., BMC Med
    Pandey et al., 2001, Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain., J. Neurochem.
    Pandey et al., 2001, Effects of chronic ethanol intake and its withdrawal on the expression and phosphorylation of the creb gene transcription factor in rat cortex., J. Pharmacol. Exp. Ther.
  • CITALOPRAM   CREB1

    Interaction Score: 1.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20643483 17548750


    Sources:
    PharmGKB

  • LITHIUM   CREB1

    Interaction Score: 0.67

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24885933


    Sources:
    PharmGKB

  • NICOTINE   CREB1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11331423


    Sources:
    NCI

  • ALCOHOL   CREB1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11181917


    Sources:
    NCI

  • Ensembl: ENSG00000118260

    • Version: 101_38

    Alternate Names:
    CREB1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: CREB1

    • Version: 18-August-2020

    Alternate Names:
    PA26864 PharmGKB ID

    Gene Info:

    Publications:
    Salloum NC et al., 2014, Towards the clinical implementation of pharmacogenetics in bipolar disorder., BMC Med
    Calati R et al., 2013, Evaluation of the role of MAPK1 and CREB1 polymorphisms on treatment resistance, response and remission in mood disorder patients., Prog Neuropsychopharmacol Biol Psychiatry
    Serretti A et al., 2011, A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression., J Affect Disord

  • NCI: CREB1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Pandey et al., 2001, Effects of chronic ethanol intake and its withdrawal on the expression and phosphorylation of the creb gene transcription factor in rat cortex., J. Pharmacol. Exp. Ther.
    Pandey et al., 2001, Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain., J. Neurochem.

  • Pharos: CREB1

    • Version: 01-February-2022

    Alternate Names:
    Cyclic AMP-responsive element-binding protein 1 Gene Name
    P16220 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

  • CarisMolecularIntelligence: CREB1

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • GO: CREB1

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR COMPLEX

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21