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CRH Gene Record

  • Summary
  • Interactions
  • Claims
  • CRH 1392 Druggable Genome

    Alternate Names:

    1392
    CORTICOTROPIN RELEASING HORMONE
    CRH
    CRF
    CRH1
    122560
    2355
    ENSG00000147571
    OTTHUMG00000164474
    PA119

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    HORMONE ACTIVITY
    DRUGGABLE GENOME

    Publications:

    Vanvugt et al., 1989, Naloxone antagonism of corticotropin-releasing hormone stimulation of prolactin secretion in rhesus monkeys., J. Clin. Endocrinol. Metab.
    Cannavò et al., 2004, Baseline and CRH-stimulated ACTH and cortisol levels after administration of the peroxisome proliferator-activated receptor-gamma ligand, rosiglitazone, in Cushing's disease., J. Endocrinol. Invest.
  • NALOXONE   CRH

    Interaction Score: 5.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2542355


    Sources:
    NCI

  • ROSIGLITAZONE   CRH

    Interaction Score: 2.69

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15279069


    Sources:
    NCI

  • Ensembl: ENSG00000147571

    • Version: 101_38

    Alternate Names:
    CRH Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: CRH

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Pang et al., 1998, A neurotensin receptor antagonist inhibits acute immobilization stress-induced cardiac mast cell degranulation, a corticotropin-releasing hormone-dependent process., J. Pharmacol. Exp. Ther.
    Schüle et al., 2001, Attenuation of HPA axis hyperactivity and simultaneous clinical deterioration in a depressed patient treated with mirtazapine., World J. Biol. Psychiatry
    Vanvugt et al., 1989, Naloxone antagonism of corticotropin-releasing hormone stimulation of prolactin secretion in rhesus monkeys., J. Clin. Endocrinol. Metab.

  • HingoraniCasas: ENSG00000147571

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000147571 Gene Symbol
    CRH Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • PharmGKB: CRH

    • Version: 18-August-2020

    Alternate Names:
    PA119 PharmGKB ID

    Gene Info:

    Publications:

  • GO: CRH

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    HORMONE ACTIVITY

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21