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CYBB Gene Record

  • Summary
  • Interactions
  • Claims
  • CYBB 1536 Druggable Genome

    Alternate Names:

    1536
    CYTOCHROME B-245 BETA CHAIN
    CYBB
    AMCBX2
    CGD
    GP91-1
    GP91-PHOX
    GP91PHOX
    IMD34
    NOX2
    p91-PHOX
    300481
    2578
    ENSG00000165168
    OTTHUMG00000033175
    P04839
    CGDX
    Cytochrome b-245 heavy chain

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

    Makino J et al., 2013, Luteolin suppresses the differentiation of THP-1 cells through the Inhibition of NOX2 mRNA expression and the membrane translocation of p47phox., J Nat Prod
  • CHRYSIN   CYBB

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23786520


    Sources:
    DTC

  • APIGENIN   CYBB

    Interaction Score: 1.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23786520


    Sources:
    DTC

  • LUTEOLIN   CYBB

    Interaction Score: 1.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23786520


    Sources:
    DTC

  • Ensembl: ENSG00000165168

    • Version: 101_38

    Alternate Names:
    CYBB Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DTC: CYBB

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Makino J et al., 2013, Luteolin suppresses the differentiation of THP-1 cells through the Inhibition of NOX2 mRNA expression and the membrane translocation of p47phox., J Nat Prod

  • HingoraniCasas: ENSG00000165168

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000165168 Gene Symbol
    CYBB Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: CYBB

    • Version: 19.3

    Alternate Names:
    ENSG00000165168 Ensembl Gene ID
    CGD Human Protein Atlas Gene Synonym
    GP91-PHOX Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

  • Pharos: CYBB

    • Version: 01-February-2022

    Alternate Names:
    Cytochrome b-245 heavy chain Gene Name
    P04839 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21