• CYSLTR2 57105 Druggable Genome

    Alternate Names:

    57105
    CYSTEINYL LEUKOTRIENE RECEPTOR 2
    CYSLTR2
    CYSLT2
    CYSLT2R
    GPCR21
    HG57
    HPN321
    KPG_011
    PSEC0146
    hGPCR21
    605666
    18274
    ENSG00000152207
    OTTHUMG00000016906
    Q9NS75
    CLTR2_HUMAN
    270
    NP_065110
    NM_020377
    CysLT<sub>2</sub> receptor
    CYSTEINYL LEUKOTRIENE RECEPTOR 2 (CYSLTR2) (HG57) (HPN321) (HGPCR21). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9NS75]
    Leukotriene CysLT2 receptor
    T74238

    Gene Info:

    GuideToPharmacology Gene Category Name Leukotriene receptors
    GuideToPharmacology Gene Category ID 35
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Type Family
    Interpro Acc IPR000276
    Uniprot Status Swiss-Prot
    Uniprot Evidence 2: Evidence at transcript level
    Interpro Name GPCR, rhodopsin-like, 7TM
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 6.38

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction against LTC<sub>4</sub> Ca<sup>2+</sup> mobilisation assay in HUVEC
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 6.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 6.38

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Details of Interaction against LTC<sub>4</sub> Ca<sup>2+</sup> mobilisation assay in HUVEC
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 6.38

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction against LTC<sub>4</sub> Ca<sup>2+</sup> mobilization assay in HUVEC
    Direct Interaction? False
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.75

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Details of Interaction against LTC<sub>4</sub> Ca<sup>2+</sup> mobilisation assay in HUVEC
    Details of Interaction againist [<sup>3</sup>H]LTD<sub>4</sub> in COS-7 cells
    Direct Interaction? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    CYSLTR2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    Q9NS75 Uniprot Accession
    CLTR2_HUMAN Uniprot Id
    ENSG00000152207 Ensembl Gene Id

    Gene Info:
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Type Family

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    CYSLTR2 Display Id
    CYSTEINYL LEUKOTRIENE RECEPTOR 2 (CYSLTR2) (HG57) (HPN321) (HGPCR21). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9NS75] Description
    ENSG00000152207 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    18274 HUGO Gene ID
    18274 HUGO Gene Symbol
    cysteinyl leukotriene receptor 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Leukotriene receptors
    GuideToPharmacology Gene Category ID 35

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000152207 Gene Symbol
    CYSLTR2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    57105 Gene ID
    CYSLT2 dGene Synonym
    CYSLT2R dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    CYSLTR2 TTD Gene Abbreviation
    T74238 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Cysteinyl leukotriene receptor 2 Gene Name
    Q9NS75 UniProt ID

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications: