• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

DCN Gene Record

  • Summary
  • Interactions
  • Claims
  • DCN 1634 Druggable Genome

    Alternate Names:

    1634
    DECORIN
    DCN
    CSCD
    DSPG2
    PG40
    PGII
    PGS2
    SLRR1B
    125255
    2705
    ENSG00000011465
    OTTHUMG00000169998

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

    Schaefer et al., 2007, Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin., Am. J. Pathol.
  • SIROLIMUS   DCN

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17200203


    Sources:
    NCI

  • Ensembl: ENSG00000011465

    • Version: 101_38

    Alternate Names:
    DCN Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: DCN

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Arai et al., 1997, Adenovirus vector-mediated gene transduction to chondrocytes: in vitro evaluation of therapeutic efficacy of transforming growth factor-beta 1 and heat shock protein 70 gene transduction., J. Rheumatol.
    Comalada et al., 2003, Decorin reverses the repressive effect of autocrine-produced TGF-beta on mouse macrophage activation., J. Immunol.
    Hering et al., 1994, Modulation of extracellular matrix gene expression in bovine high-density chondrocyte cultures by ascorbic acid and enzymatic resuspension., Arch. Biochem. Biophys.

  • HingoraniCasas: ENSG00000011465

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000011465 Gene Symbol
    DCN Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21