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DIABLO Gene Record

  • Summary
  • Interactions
  • Claims
  • DIABLO 56616

    Alternate Names:

    56616
    DIABLO IAP-BINDING MITOCHONDRIAL PROTEIN
    DIABLO
    DFNA64
    SMAC
    605219
    21528
    ENSG00000184047
    OTTHUMG00000157014

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Aziz et al., 2005, Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?, FASEB J.
    Aziz et al., Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin., Photochem. Photobiol.
    Essmann et al., 2004, Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event., Cancer Res.
    Zhang et al., 2004, Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways., Mol. Cancer Ther.
    Wang et al., 2003, Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms., Mol. Pharmacol.
    Chow et al., 2003, Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation., Biochem. Pharmacol.
  • CLADRIBINE   DIABLO

    Interaction Score: 2.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12948851


    Sources:
    NCI

  • STAUROSPORINE   DIABLO

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15466201 14985459


    Sources:
    NCI

  • UCN-01   DIABLO

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12488556


    Sources:
    NCI

  • RESVERATROL   DIABLO

    Interaction Score: 1.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15837718 15469386


    Sources:
    NCI

  • Ensembl: ENSG00000184047

    • Version: 101_38

    Alternate Names:
    DIABLO Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: DIABLO

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Zhang et al., 2004, Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways., Mol. Cancer Ther.
    Essmann et al., 2004, Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event., Cancer Res.
    Miao et al., 2003, Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703., Eur. J. Biochem.

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21