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DPYS Gene Record

  • Summary
  • Interactions
  • Claims
  • DPYS 1807

    Alternate Names:

    1807
    DIHYDROPYRIMIDINASE
    DPYS
    DHP
    DHPase
    613326
    3013
    ENSG00000147647
    OTTHUMG00000164891
    PA146
    Q14117

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Kummer D et al., 2015, Dihydropyrimidinase and β-ureidopropionase gene variation and severe fluoropyrimidine-related toxicity., Pharmacogenomics
    Hasinoff, Enzymatic ring-opening reactions of the chiral cardioprotective agent (+) (S)-ICRF-187 and its (-) (R)-enantiomer ICRF-186 by dihydropyrimidine amidohydrolase., Drug Metab. Dispos.
  • DEXRAZOXANE   DPYS

    Interaction Score: 6.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7902252


    Sources:
    NCI

  • ATENOLOL   DPYS

    Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • FLUOROURACIL   DPYS

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26244261


    Sources:
    PharmGKB

  • Ensembl: ENSG00000147647

    • Version: 101_38

    Alternate Names:
    DPYS Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: DPYS

    • Version: 18-August-2020

    Alternate Names:
    PA146 PharmGKB ID

    Gene Info:

    Publications:
    Kummer D et al., 2015, Dihydropyrimidinase and β-ureidopropionase gene variation and severe fluoropyrimidine-related toxicity., Pharmacogenomics

  • NCI: DPYS

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Hasinoff, Enzymatic ring-opening reactions of the chiral cardioprotective agent (+) (S)-ICRF-187 and its (-) (R)-enantiomer ICRF-186 by dihydropyrimidine amidohydrolase., Drug Metab. Dispos.

  • HumanProteinAtlas: DPYS

    • Version: 19.3

    Alternate Names:
    ENSG00000147647 Ensembl Gene ID
    DHPase Human Protein Atlas Gene Synonym
    Dihydropyrimidinase Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21