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EEF2 Gene Record

  • Summary
  • Interactions
  • Claims
  • EEF2 1938 Druggable Genome

    Alternate Names:

    1938
    EUKARYOTIC TRANSLATION ELONGATION FACTOR 2
    EEF2
    EEF-2
    EF-2
    EF2
    SCA26
    130610
    3214
    ENSG00000167658
    OTTHUMG00000181790
    P13639
    Elongation factor 2

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Miscellaneous
    Target Subclass elongation factor
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    KINASE
    DRUGGABLE GENOME

    Publications:

    Schneider-Poetsch T et al., 2010, Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin., Nat Chem Biol
  • LACTIMIDOMYCIN   EEF2

    Interaction Score: 30.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20118940


    Sources:
    DTC

  • OPORTUZUMAB MONATOX   EEF2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name VB4-845,Proxinium, Vicinium
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • DENILEUKIN DIFTITOX   EEF2

    Interaction Score: 3.86

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Elongation factor 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CYCLOHEXIMIDE   EEF2

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20118940


    Sources:
    DTC

  • Ensembl: ENSG00000167658

    • Version: 101_38

    Alternate Names:
    EEF2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P13639

    • Version: January-2014

    Alternate Names:
    EEF2 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Miscellaneous
    Target Subclass elongation factor

    Publications:

  • DTC: EEF2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Schneider-Poetsch T et al., 2010, Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin., Nat Chem Biol

  • ChemblInteractions: EF2

    • Version: chembl_23

    Alternate Names:
    EF2 GENE_SYMBOL
    EEF2 GENE_SYMBOL
    Elongation factor 2 UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000167658

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000167658 Gene Symbol
    EEF2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: EEF2

    • Version: 01-February-2022

    Alternate Names:
    Elongation factor 2 Gene Name
    P13639 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21