• EPHA8 2046 Druggable Genome

    Alternate Names:

    2046
    EPH RECEPTOR A8
    EPHA8
    EEK
    EK3
    HEK3
    176945
    3391
    ENSG00000070886
    OTTHUMG00000002892
    P29322
    EPHA8_HUMAN
    KIAA1459
    EPH-like kinase 3
    Tyrosine-protein kinase receptor EEK
    Ephrin type-A receptor 8
    EPH- and ELK-related kinase
    1828
    EPHRIN TYPE-A RECEPTOR 8 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR EEK) (EPH-AND ELK-RELATED KINASE) (HEK3). [SOURCE:UNIPROT/SWISSPROT;ACC:P29322]
    NP_001006944
    NM_001006943
    BE0009440

    Gene Info:

    Uniprot Status Swiss-Prot
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Acc IPR001245
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    GuideToPharmacology Gene Category Name Type XIII RTKs: Ephrin receptor family
    GuideToPharmacology Gene Category ID 327
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
  • Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15850105


    Sources:
    NCI

  • Interaction Score: 0.34

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Ephrin receptor inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.13

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank