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ERCC6 Gene Record

  • Summary
  • Interactions
  • Claims
  • ERCC6 2074

    Alternate Names:

    2074
    ERCC EXCISION REPAIR 6, CHROMATIN REMODELING FACTOR
    ERCC6
    ARMD5
    CKN2
    COFS
    COFS1
    CSB
    POF11
    RAD26
    UVSS1
    609413
    3438
    ENSG00000225830
    OTTHUMG00000018195
    CSB-PGBD3

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Dianov et al., 1997, Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells., Nucleic Acids Res.
    Yin et al., 1999, Effect of dextromethorphan, a NMDA antagonist, on DNA repair in rat photochemical thrombotic cerebral ischemia., Brain Res.
  • DEXTROMETHORPHAN   ERCC6

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9974119


    Sources:
    NCI

  • CYCLOSPORINE   ERCC6

    Interaction Score: 1.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9278484


    Sources:
    NCI

  • Ensembl: ENSG00000225830

    • Version: 101_38

    Alternate Names:
    ERCC6 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: ERCC6

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Yin et al., 1999, Effect of dextromethorphan, a NMDA antagonist, on DNA repair in rat photochemical thrombotic cerebral ischemia., Brain Res.
    Kyng et al., 2003, The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells., Oncogene
    Dianov et al., 1997, Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells., Nucleic Acids Res.

  • Tempus: ERCC6

    • Version: 11-November-2018

    Alternate Names:
    ERCC6 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21