ESR2 |
2100 |
ESTROGEN RECEPTOR 2 |
ER-BETA |
ESR-BETA |
ESRB |
ESTRB |
Erb |
NR3A2 |
601663 |
3468 |
ENSG00000140009 |
OTTHUMG00000141306 |
Q92731 |
ESTROGEN RECEPTOR BETA (ER-BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q92731] |
ESTROGEN RECEPTOR BETA |
ESR2_HUMAN |
PA27886 |
Nuclear receptor subfamily 3 group A member 2 |
T80896 |
ODG8 |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
Human Readable Name | DRUGGABLE GENOME |
Initial Gene Query | NR3A2 |
Counted Citations from 1950-2000 | 3987 |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
Interpro Type | Domain |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR000536 |
Interpro Short Name | Nucl_hrmn_rcpt_lig-bd_core |
Uniprot Evidence | 1: Evidence at protein level |
Target Main Class | Receptors |
Gene Biotype | PROTEIN_CODING |
NUCLEAR HORMONE RECEPTOR |
DRUGGABLE GENOME |
TRANSCRIPTION FACTOR |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Estrogen receptor beta agonist |
Trial Name | AUS-131 |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor beta agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Estrogen receptor beta agonist |
agonist (activating) |
Trial Name | MF101 ,Menerba |
Novel drug target | Established target |
Mechanism of Interaction | Estrogen receptor beta agonist |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor agonist |
Direct Interaction | yes |
Trial Name | MK-6913 |
n/a |
Trial Name | conjugated estrogens/medroxyprogesterone acetate,Prempro, Premphase |
Novel drug target | Established target |
Trial Name | oral contraceptive,Pill-Plus |
modulator |
Trial Name | fispemifene, HM-101 |
Novel drug target | Established target |
Mechanism of Interaction | Estrogen receptor modulator |
n/a |
Trial Name | Evista |
Novel drug target | Established target |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Estrogen receptor modulator |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor agonist |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor agonist |
Direct Interaction | yes |
n/a |
Trial Name | TAS-108 |
Novel drug target | Established target |
n/a |
Novel drug target | Established target |
Trial Name | A-007 |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Estrogen receptor beta |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Estrogen receptor agonist |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | bazedoxifene, bazedoxifene/conjugated estrogens, TSE-424,Viviant, Aprela, Conbriza |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Estrogen receptor beta agonist |
modulator |
Trial Name | ospemifene,Ophena |
Novel drug target | Established target |
Direct Interaction | yes |
antagonist (inhibitory) |
Notes | |
Mechanism of Interaction | Estrogen receptor antagonist |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Trial Name | Bio-E-Gel, estradiol,Elestrin |
Novel drug target | Established target |
Trial Name | drospirenone plus estradiol,Angeliq |
n/a |
Novel drug target | Established target |
Trial Name | atamestane-plus-toremifene |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Estrogen receptor agonist |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor beta modulator |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor modulator |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Estrogen receptor beta modulator |
Direct Interaction | yes |
ESR2 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
2100 | Entrez Gene ID |
Initial Gene Query | NR3A2 |
Counted Citations from 1950-2000 | 3987 |
NUCLEAR HORMONE RECEPTOR |
ESR2 | Display Id |
ESTROGEN RECEPTOR BETA (ER-BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q92731] | Description |
ENSG00000140009 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ESR2 | Uniprot Gene Name |
ENSG00000140009 | Ensembl Gene Id |
2100 | Entrez Gene Id |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Human Readable Name | DRUGGABLE GENOME |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME |
ENSG00000140009 | Ensembl Gene Id |
Q92731 | Uniprot Accession |
2100 | Entrez Gene Id |
Target Subclass | Nuclear receptor |
Target Main Class | Receptors |
ESR2 | Gene Symbol |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
PA27886 | PharmGKB ID |
ESR2 | TTD Gene Abbreviation |
T80896 | TTD Target ID |
ENSG00000140009 | Gene Symbol |
ESR2 | Ensembl Id |
DRUGGABLE GENOME |
ESR2 | Gene Symbol |
NR3A2 | GENE_SYMBOL |
ESR2 | GENE_SYMBOL |
Estrogen receptor beta | UNIPROT |
ESTRB | GO Gene Synonym |
NR3A2 | GO Gene Synonym |
NUCLEAR HORMONE RECEPTOR |
2100 | Gene ID |
ER-BETA | dGene Synonym |
ESR-BETA | dGene Synonym |
NUCLEAR HORMONE RECEPTOR |
Estrogen receptor beta | Gene Name |
Q92731 | UniProt ID |
NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR |