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FNTB 2342 Druggable Genome
Alternate Names:
2342 FARNESYLTRANSFERASE, CAAX BOX, BETA FNTB FPTB 134636 3785 ENSG00000257365 OTTHUMG00000142811 P49356 CAAX farnesyltransferase subunit beta Ras proteins prenyltransferase subunit beta FTase-beta Protein farnesyltransferase subunit beta BE0002372 FNTB_HUMAN ENSG00000125954 PROTEIN FARNESYLTRANSFERASE BETA SUBUNIT (EC 2.5.1.58) (CAAX FARNESYLTRANSFERASE BETA SUBUNIT) (RAS PROTEINS PRENYLTRANSFERASE BETA) (FTASE-BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49356] 2826 PA28202 NM_002028 NP_002019 Gene Info:
Target Class Enzymes Target Subclass EC:2.5.1.58 Uniprot Status Swiss-Prot Interpro Short Name Prenyltrans Interpro Acc IPR001330 Human Readable Name DRUGGABLE GENOME Interpro Type Repeat Interpro Name Prenyltransferase/squalene oxidase Uniprot Evidence 1: Evidence at protein level Gene Biotype PROTEIN_CODING GuideToPharmacology Gene Category Name 2.5.1.58 Protein farnesyltransferase GuideToPharmacology Gene Category ID 898 Gene Categories: Category Details
DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 6.31
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Interaction Score: 6.31
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Interaction Score: 6.31
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
Interaction Score: 5.26
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction? True Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Score: 2.71
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Protein farnesyltransferase inhibitor Direct Interaction yes -
Interaction Score: 1.8
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Interaction Score: 0.16
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Interaction Score: 0.13
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- Version: 101_38
Alternate Names:
FNTB Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
FNTB Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:2.5.1.58 Publications:
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- Version: 26-July-2011
Alternate Names:
FNTB Display Id ENSG00000125954 Ensembl Gene Id PROTEIN FARNESYLTRANSFERASE BETA SUBUNIT (EC 2.5.1.58) (CAAX FARNESYLTRANSFERASE BETA SUBUNIT) (RAS PROTEINS PRENYLTRANSFERASE BETA) (FTASE-BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49356] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
P49356 Uniprot Accession FNTB Uniprot Gene Name PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA Uniprot Protein Name Gene Info:
Uniprot Status Swiss-Prot Interpro Short Name Prenyltrans Interpro Acc IPR001330 Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
3785 HUGO Gene ID 3785 HUGO Gene Symbol farnesyltransferase, CAAX box, beta HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name 2.5.1.58 Protein farnesyltransferase GuideToPharmacology Gene Category ID 898 Gene Categories:
ENZYME Publications:
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Alternate Names:
PA28202 PharmGKB ID Gene Info:
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Alternate Names:
FNTB DrugBank Gene Name P49356 UniProt Accession 2342 Entrez Gene Id Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000257365 Gene Symbol FNTB Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
FNTB GENE_SYMBOL Protein farnesyltransferase subunit beta UNIPROT CAAX farnesyltransferase subunit beta UNIPROT Gene Info:
Publications:
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Alternate Names:
FNTB Gene Symbol Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: