DGIdb - FOS Gene Record

FOS 2353 Druggable GenomeDrug Resistance

Alternate Names:

2353
FOS PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT
FOS
AP-1
C-FOS
p55
164810
3796
ENSG00000170345
OTTHUMG00000171774
BE0001126
P01100
G0S7
Proto-oncogene c-Fos

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

DRUG RESISTANCE
TRANSCRIPTION FACTOR BINDING
DRUGGABLE GENOME
TRANSCRIPTION FACTOR

Publications:

Takemura et al., 2001, GABA B receptor-mediated effects on expression of c-Fos in rat trigeminal nucleus following high- and low-intensity afferent stimulation., Neuroscience
Nagy et al., 2009, The effect of LMWH (Nadroparin) on tumor progression., Pathol. Oncol. Res.
Sustar et al., Suppression of membrane microvesiculation--a possible anticoagulant and anti-tumor progression effect of heparin., Blood Cells Mol. Dis.
Lampugnani et al., 1990, Thrombin induces c-fos expression in cultured human endothelial cells by a Ca2(+)-dependent mechanism., Blood
Hui et al., 1998, Inhibition of activator protein 1 activity by paclitaxel suppresses interleukin-1-induced collagenase and stromelysin expression by bovine chondrocytes., Arthritis Rheum.
Murphy et al., 2006, Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice., Brain Res.
Kukushkin et al., [Effect of anisomycin on activation of early response genes c-fos, c-jun, Egr-1 in cells transformed by E1A and cHa-ras oncogenes]., Mol. Biol. (Mosk.)
Bucci et al., Effects of age on pilocarpine-induced c-fos expression in rat hippocampus and cortex., Neurobiol. Aging
Tanaka et al., 1997, Changes in glutamate receptors, c-fos mRNA expression and activator protein-1 (AP-1) DNA binding activity in the brain of phenobarbital-dependent and -withdrawn rats., Brain Res.
Mäkelä et al., 1995, Phytoestrogens are partial estrogen agonists in the adult male mouse., Environ. Health Perspect.
Ko et al., 1993, Action of dihydropyridine calcium antagonists on early growth response gene expression and cell growth in vascular smooth muscle cells., J. Hypertens.
Burdman et al., 2001, Bromocriptine and the expression of c-myc and c-fos in human prolactinomas., Neurol. Res.

NADROPARIN FOS

Interaction Score: 3.87

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
19757196 19261492

Sources:
DrugBank
ANTIBIOTIC FOS

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15773551

Sources:
NCI
BACLOFEN FOS

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11301212

Sources:
NCI
PILOCARPINE FOS

Interaction Score: 0.74

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9661997

Sources:
NCI
NIMODIPINE FOS

Interaction Score: 0.49

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8301097

Sources:
NCI
DAIDZEIN FOS

Interaction Score: 0.45

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8593857

Sources:
NCI
THROMBIN FOS

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2119237

Sources:
NCI
BROMOCRIPTINE FOS

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11680511

Sources:
NCI
PHENOBARBITAL FOS

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9187311

Sources:
NCI
PACLITAXEL FOS

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9588740

Sources:
NCI
ALCOHOL FOS

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16750178

Sources:
NCI

Ensembl: ENSG00000170345
- Version: 101_38
Alternate Names:

FOS Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0001126

Version: 5.1.7

Alternate Names:

FOS DrugBank Gene Name

P01100 UniProt Accession

2353 Entrez Gene Id

Gene Info:

Publications:

Sustar et al., Suppression of membrane microvesiculation--a possible anticoagulant and anti-tumor progression effect of heparin., Blood Cells Mol. Dis.

Nagy et al., 2009, The effect of LMWH (Nadroparin) on tumor progression., Pathol. Oncol. Res.

NCI: FOS

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Ko et al., 1993, Action of dihydropyridine calcium antagonists on early growth response gene expression and cell growth in vascular smooth muscle cells., J. Hypertens.

Buritova et al., 2001, Urethane anaesthesia could partly mask antinociceptive effects of non-steroidal anti-inflammatory drugs: a spinal c-Fos protein study., Brain Res.

Silvers et al., The role of JNK and p38 MAPK activities in UVA-induced signaling pathways leading to AP-1 activation and c-Fos expression., Neoplasia

HingoraniCasas: ENSG00000170345
- Version: 31-May-2017
Alternate Names:

ENSG00000170345 Gene Symbol

FOS Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: FOS
- Version: 03-September-2020
Alternate Names:

Proto-oncogene c-Fos Gene Name

P01100 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications:
GO: FOS
- Version: 05-September-2020
Alternate Names:

G0S7 GO Gene Synonym

Gene Info:

Gene Categories:

DRUG RESISTANCE, TRANSCRIPTION FACTOR BINDING

Publications:

FOS	DrugBank Gene Name
P01100	UniProt Accession
2353	Entrez Gene Id

FOS Gene Record

FOS 2353 Druggable GenomeDrug Resistance

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 19757196 19261492

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15773551

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11301212

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9661997

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8301097

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8593857

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2119237

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11680511

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9187311

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9588740

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16750178

Sources: NCI

Ensembl: ENSG00000170345

Alternate Names: FOS Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0001126

Alternate Names: FOS DrugBank Gene Name P01100 UniProt Accession 2353 Entrez Gene Id

Gene Info:

Publications: Sustar et al., Suppression of membrane microvesiculation--a possible anticoagulant and anti-tumor progression effect of heparin., Blood Cells Mol. Dis. Nagy et al., 2009, The effect of LMWH (Nadroparin) on tumor progression., Pathol. Oncol. Res.

NCI: FOS

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000170345

Alternate Names: ENSG00000170345 Gene Symbol FOS Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

Pharos: FOS

Alternate Names: Proto-oncogene c-Fos Gene Name P01100 UniProt ID

Gene Info:

Gene Categories: TRANSCRIPTION FACTOR

Publications:

GO: FOS

Alternate Names: G0S7 GO Gene Synonym

Gene Info:

Gene Categories: DRUG RESISTANCE, TRANSCRIPTION FACTOR BINDING

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
19757196 19261492

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
15773551

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11301212

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9661997

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8301097

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8593857

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2119237

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11680511

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9187311

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9588740

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16750178

Sources:
NCI

Alternate Names:

FOS Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

FOS DrugBank Gene Name

P01100 UniProt Accession

2353 Entrez Gene Id

Publications:

Sustar et al., Suppression of membrane microvesiculation--a possible anticoagulant and anti-tumor progression effect of heparin., Blood Cells Mol. Dis.

Nagy et al., 2009, The effect of LMWH (Nadroparin) on tumor progression., Pathol. Oncol. Res.

Alternate Names:

ENSG00000170345 Gene Symbol

FOS Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

Proto-oncogene c-Fos Gene Name

P01100 UniProt ID

Gene Categories:

TRANSCRIPTION FACTOR

Alternate Names:

G0S7 GO Gene Synonym

Gene Categories:

DRUG RESISTANCE, TRANSCRIPTION FACTOR BINDING