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FTO Gene Record

  • Summary
  • Interactions
  • Claims
  • FTO 79068

    Alternate Names:

    79068
    FTO, ALPHA-KETOGLUTARATE DEPENDENT DIOXYGENASE
    FTO
    ALKBH9
    BMIQ14
    GDFD
    610966
    24678
    ENSG00000140718
    OTTHUMG00000158780
    PA152208656
    FTO ALPHA-KETOGLUTARATE DEPENDENT DIOXYGENASE
    Q9C0B1
    Alpha-ketoglutarate-dependent dioxygenase FTO

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Kim HS et al., 2017, A coding variant in <i>FTO</i> confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD., Gut
    Pineda-Tenor D et al., 2014, FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients., BMC Med
    Zhou H et al., 2020, Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits., Nat Neurosci
  • AZATHIOPRINE   FTO

    Interaction Score: 0.99

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27558924


    Sources:
    PharmGKB

  • RIBAVIRIN   FTO

    Interaction Score: 0.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25367448


    Sources:
    PharmGKB

  • MERCAPTOPURINE   FTO

    Interaction Score: 0.69

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27558924


    Sources:
    PharmGKB

  • ATENOLOL   FTO

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ALCOHOL   FTO

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    32451486


    Sources:
    PharmGKB

  • Ensembl: ENSG00000140718

    • Version: 101_38

    Alternate Names:
    FTO Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: FTO

    • Version: 18-August-2020

    Alternate Names:
    PA152208656 PharmGKB ID

    Gene Info:

    Publications:
    Kim HS et al., 2017, A coding variant in <i>FTO</i> confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD., Gut
    Pineda-Tenor D et al., 2014, FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients., BMC Med
    Zhou H et al., 2020, Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits., Nat Neurosci

  • Pharos: FTO

    • Version: 01-February-2022

    Alternate Names:
    Alpha-ketoglutarate-dependent dioxygenase FTO Gene Name
    Q9C0B1 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21