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GABPA Gene Record

  • Summary
  • Interactions
  • Claims
  • GABPA 2551

    Alternate Names:

    2551
    GA BINDING PROTEIN TRANSCRIPTION FACTOR ALPHA SUBUNIT
    GABPA
    E4TF1-60
    E4TF1A
    NFT2
    NRF2
    NRF2A
    RCH04A07
    600609
    4071
    ENSG00000154727
    OTTHUMG00000078443
    GA BINDING PROTEIN TRANSCRIPTION FACTOR SUBUNIT ALPHA
    Q06546
    GA-binding protein alpha chain

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    TRANSCRIPTION FACTOR

    Publications:

    Tanigawa et al., 2007, Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin., Free Radic. Biol. Med.
    Cho et al., 2008, Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: implication to cancer cell resistance., Cancer Lett.
    Louhelainen et al., 2006, Lipoic acid supplementation prevents cyclosporine-induced hypertension and nephrotoxicity in spontaneously hypertensive rats., J. Hypertens.
  • CYCLOSPORINE   GABPA

    Interaction Score: 0.66

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16612258


    Sources:
    NCI

  • QUERCETIN   GABPA

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17462537


    Sources:
    NCI

  • CISPLATIN   GABPA

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18036733


    Sources:
    NCI

  • Ensembl: ENSG00000154727

    • Version: 101_38

    Alternate Names:
    GABPA Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: GABPA

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Tanigawa et al., 2007, Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin., Free Radic. Biol. Med.
    Purdom-Dickinson et al., 2007, Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor., J. Mol. Cell. Cardiol.
    Cho et al., 2008, Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: implication to cancer cell resistance., Cancer Lett.

  • Pharos: GABPA

    • Version: 01-February-2022

    Alternate Names:
    GA-binding protein alpha chain Gene Name
    Q06546 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21