DGIdb - GFAP Gene Record

GFAP 2670

Alternate Names:

2670
GLIAL FIBRILLARY ACIDIC PROTEIN
GFAP
ALXDRD
137780
4235
ENSG00000131095
OTTHUMG00000179866

Gene Info:

Gene Biotype	PROTEIN_CODING

(0 More Sources)

Gene Categories: Category Details

Publications:

Levi et al., 1993, Human immunodeficiency virus coat protein gp120 inhibits the beta-adrenergic regulation of astroglial and microglial functions., Proc. Natl. Acad. Sci. U.S.A.
Woiciechowsky et al., 2004, Brain-IL-1 beta triggers astrogliosis through induction of IL-6: inhibition by propranolol and IL-10., Med. Sci. Monit.
Whitehead et al., 2007, Effects of triflusal and aspirin in a rat model of cerebral ischemia., Stroke
Jean Harry et al., 2003, Differential modulation of hippocampal chemical-induced injury response by ebselen, pentoxifylline, and TNFalpha-, IL-1alpha-, and IL-6-neutralizing antibodies., J. Neurosci. Res.
Suárez et al., 2000, Neuronal and astroglial response to pre- and perinatal exposure to delta-9-tetra- hydrocannabinol in the rat substantia nigra., Dev. Neurosci.
Mader et al., 2004, Dual mode of signalling of the axotomy reaction: retrograde electric stimulation or block of retrograde transport differently mimic the reaction of motoneurons to nerve transection in the rat brainstem., J. Neurotrauma
Pozas et al., 1999, Fra-1 immunoreactivity in the rat brain during normal postnatal development and after injury in adulthood., Neurosci. Res.
Luthman et al., 1991, Combined lead acetate and disulfiram treatment-induced alterations of glial fibrillary acidic protein (GFA) immunoreactive astrocytes in brain smears., Toxicology
Oh et al., 1995, Acidic pH rapidly increases immunoreactivity of glial fibrillary acidic protein in cultured astrocytes., Glia
Wofchuk et al., 1995, Age-dependent changes in the regulation by external calcium ions of the phosphorylation of glial fibrillary acidic protein in slices of rat hippocampus., Brain Res. Dev. Brain Res.
Du et al., 1999, Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord., Exp. Neurol.
Guntinas-Lichius et al., 1997, Nimodipine maintains in vivo the increase in GFAP and enhances the astroglial ensheathment of surviving motoneurons in the rat following permanent target deprivation., J. Neurocytol.
Seoane et al., 1999, Degeneration and gliosis in rat retina and central nervous system following 3,3'-iminodipropionitrile exposure., Brain Res.
Sharma et al., 1991, Phorbol-12-myristate-13-acetate (PMA) and inhibitors of protein kinase C alter glial fibrillary acidic protein (GFAP) mRNA levels., Glia
Pittman et al., Immunohistochemical changes in the mouse striatum induced by the pyrethroid insecticide permethrin., Int. J. Toxicol.
Massengale et al., 2002, Carbohydrate source influences gelatinase production by mouse astrocytes in vitro., Glia
Melcangi et al., 1997, Astrocyte-neuron interactions in vitro: role of growth factors and steroids on LHRH dynamics., Brain Res. Bull.
Yanagisawa et al., 2000, Astrocyte differentiation of fetal neuroepithelial cells by interleukin-11 via activation of a common cytokine signal transducer, gp130, and a transcription factor, STAT3., J. Neurochem.
Hoyk et al., 2004, Dehydroepiandrosterone regulates astroglia reaction to denervation of olfactory glomeruli., Glia
Kim et al., 2004, Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo., J. Neurochem.
Suzuki et al., 2004, Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex., Proc. Natl. Acad. Sci. U.S.A.
Borlongan et al., 2000, Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia., FASEB J.
Oppelt et al., 2004, Role of intracellular calcium stores on the effect of metabotropic glutamate receptors on phosphorylation of glial fibrillary acidic protein in hippocampal slices from immature rats., Neurochem. Res.
Ogawa et al., 1985, Transient expression of glial fibrillary acidic protein in developing oligodendrocytes in vitro., Brain Res.
Okere et al., 2004, Capsaicin increases GFAP and glutamine synthetase immunoreactivity in rat arcuate nucleus and median eminence., Neuroreport
Silva-Araújo et al., 1995, Expression of glial fibrillary acidic protein in the rat retina after exposure to psychostimulants., Retina (Philadelphia, Pa.)
Armstrong et al., 2004, Repeated amphetamine treatment causes a persistent elevation of glial fibrillary acidic protein in the caudate-putamen., Eur. J. Pharmacol.
Luo et al., 1999, Dopamine stimulates redox-tyrosine kinase signaling and p38 MAPK in activation of astrocytic C6-D2L cells., Brain Res.
Kiaei et al., 2005, Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis., Exp. Neurol.

SORBITOL GFAP

Interaction Score: 1.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11968061

Sources:
NCI
PERMETHRIN GFAP

Interaction Score: 1.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14555407

Sources:
NCI
FADROZOLE GFAP

Interaction Score: 0.99

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15390121

Sources:
NCI
DEMECOLCINE GFAP

Interaction Score: 0.82

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3886082

Sources:
NCI
OPRELVEKIN GFAP

Interaction Score: 0.82

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10737606

Sources:
NCI
DRONABINOL GFAP

Interaction Score: 0.62

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10965147

Sources:
NCI
AMPHETAMINE GFAP

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7569352 15044042

Sources:
NCI
PIOGLITAZONE GFAP

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15649489

Sources:
NCI
CAPSAICIN GFAP

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15076747

Sources:
NCI
NIMODIPINE GFAP

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9192289

Sources:
NCI
PROPRANOLOL GFAP

Interaction Score: 0.31

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15328477

Sources:
NCI
PRASTERONE GFAP

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14973190

Sources:
NCI
METHIMAZOLE GFAP

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10375702

Sources:
NCI
NIFEDIPINE GFAP

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7615340 7600665 10222112

Sources:
NCI
MELATONIN GFAP

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10877823

Sources:
NCI
CAFFEINE GFAP

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15260132

Sources:
NCI
STAUROSPORINE GFAP

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1720762

Sources:
NCI
ISOPROTERENOL GFAP

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8381971

Sources:
NCI
COLCHICINE GFAP

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15307907 10211779

Sources:
NCI
PENTOXIFYLLINE GFAP

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12898537

Sources:
NCI
DISULFIRAM GFAP

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1992564

Sources:
NCI
LITHIUM GFAP

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15056276

Sources:
NCI
GENISTEIN GFAP

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10629745

Sources:
NCI
PROGESTERONE GFAP

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9370212

Sources:
NCI
ASPIRIN GFAP

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17194886

Sources:
NCI

Ensembl: ENSG00000131095
- Version: 101_38
Alternate Names:

GFAP Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

NCI: GFAP

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Woiciechowsky et al., 2004, Brain-IL-1 beta triggers astrogliosis through induction of IL-6: inhibition by propranolol and IL-10., Med. Sci. Monit.

Whitehead et al., 2007, Effects of triflusal and aspirin in a rat model of cerebral ischemia., Stroke

Pittman et al., Immunohistochemical changes in the mouse striatum induced by the pyrethroid insecticide permethrin., Int. J. Toxicol.

GFAP Gene Record

GFAP 2670

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11968061

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14555407

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15390121

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3886082

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10737606

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10965147

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7569352 15044042

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15649489

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15076747

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9192289

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15328477

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14973190

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10375702

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7615340 7600665 10222112

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10877823

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15260132

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1720762

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8381971

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

n/a

PMIDs:
11968061

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14555407

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15390121

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
3886082

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10737606

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10965147

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7569352 15044042

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15649489

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15076747

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9192289

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15328477

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14973190

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10375702

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7615340 7600665 10222112

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10877823

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15260132

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1720762

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8381971

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15307907 10211779

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12898537

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1992564

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15056276

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10629745

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9370212

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
17194886

Sources:
NCI

Alternate Names:

GFAP Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING